Label antibodies, small molecules, proteins, or peptides with IVISense NIR fluorescent dyes.
PerkinElmer’s IVISense™ fluorescent dyes (VivoTag®) for labeling antibodies, small molecules, proteins, or peptides are designed specifically to enable customized development of novel superbright fluorescent imaging agents. Dye properties, such as excellent brightness, hydrolytic stability, and photostability, as well as selection for minimal interaction with biological tissue for no potential loss of specificity, have been optimized and validated for use in in vivo or in vitro imaging.
Available as NHS esters or maleimide reactive dyes for conjugation to either free amine (-NH3) or free thiol (-SH) containing molecules. Conjugate an optimal 1-3 dyes onto your protein or choose self-quenching dyes to make your own custom fluorogenic probes.
For research use only. Not for use in diagnostic procedures.
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IVISense 750 MAL fluorescent dye is a thiol (-SH, sulfhydryl) thiol-reactive near-infrared fluorochrome for labeling free cysteines or thiol groups on small molecules via maleimide chemistry. Its superior brightness makes it particularly well suited for the labeling of thiol and cysteine containing molecules for a wide range of imaging applications. It is optimized for use with IVIS® fluorescence imaging systems with expanded wavelength capabilities to enable quantitative imaging of up to four channels and four different biomarkers of interest in vivo. Unit size 5 mg.
|IVISense NHS FLUORESCENT DYES|
|IVISense 645 NHS||643/660||Suitable for labeling free amines (typically lysine residues)|
|IVISense 680 NHS||665/688|
|IVISense 800 NHS||785/810|
|IVISense MAL FLUORESCENT DYES|
|IVISense 645 MAL||643/660||Suitable for labeling free thiols (typically cysteine residues)|
|IVISense 680 MAL||665/688|
|IVISense SELF-QUENCHING DYES|
|IVISense 680 NHS||673/691||When a protein is labeled with multiple IVISense Self-Quenching Dye molecules, there is a shift in the absorbance of the dye, which will reduce the signal. Only choose IVISense Self-Quenching Dyes if your labeling ratio of dye: protein will be 1:1. If multiple dyes are to be conjugated onto your protein, a non-self-quenching IVISense Dye should be used. NHS dyes are suitable for labeling free amines (typically lysine residues), while MAL dyes are suitable for labeling free thiols (typically cysteine residues).|
|IVISense 750 NHS||750/775|
|IVISense 750 MAL||750/775|
|Optical Imaging Classification||Fluorescence Imaging|
|Product Brand Name||IVISense|
|Quantity in a Package Amount||1.0 Units|
|Shipping Condition||Blue Ice|
|Unit Size||5 mg|