IVISense™ 2-DeoxyGlucosone (DG) (XenoLight™ 2-DG) fluorescent imaging probes in RediJect™ Solution enable in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, these probes have been designed to contain four 2-DG molecules per dye molecule.
IVISense 2-DG probes are available in either 1 or 4 vial quantities and come in a convenient, ready-to-use injectable format.
For research use only. Not for use in diagnostic procedures.
true falseIVISense 2-DG control dye in RediJect Solutions is a non-reactive dye that can be used as a negative control when using the IVISense 2-DG-750 fluorescent imaging probe.
| Fluorescent Agent Type | Targeted |
|---|---|
| Optical Imaging Classification | Fluorescence Imaging |
| Product Brand Name | IVISense |
| Shipping Condition | Blue Ice |
| Therapeutic Area | Arthritis, Inflammation, Oncology/Cancer |
| Unit Size | 1 |
| Wave Length | 750 nm |
Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And our hard-earned expertise makes us a trusted provider of pre-clinical imaging solutions— with more than 9,000 peer reviewed articles as proof.
Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into disease processes and treatment effects. Designing an effective study from the beginning can help save time and resources.
Learn about several important best practices, from proper probe selection to study design to imaging technique tips and tricks needed to generate meaningful biological information from your in vivo fluorescence imaging studies.
XenoLight RediJect 2-DeoxyGlucosone (DG)-750 is a fluorescent,probe for in vivo targeting of tumors that typically exhibit elevated,glucose uptake rate in comparison to surrounding tissues. To achieve,maximum glucose targeting and enhanced tumor uptake, the probe,has been designed to contain four 2-DG molecules per dye molecule.,As indicated in Figure 1, RediJect 2-DG-750 probe showed specific,accumulation to LL-2 tumors shortly after delivery. In addition, specific,tumor labeling with the RediJect 2-DG-750 probe has also been,demonstrated with Breast (MDA-MB-231) Prostate (PC-3M) and Lung,(NCI-H460) tumors, further validating the utility of this probe as a generic fluorescence reagent for in vivo tumor targeting.
The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick and efficient drug screening and evaluation. Read this White Paper to learn how preclinical in vivo imaging helps to ensure that smart choices are made by providing Go/No-Go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.
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