The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
The IVIS Lumina III is capable of imaging both fluorescent and bioluminescent reporters. The system is equipped with up to 26 filter sets that can be used to image reporters that emit from green to near-infrared. Superior spectral unmixing can be achieved by Lumina III’s optional high resolution short cut off filters.
Features and Benefits
Market trusted technology offering the fullest suite of leading imaging technologies, reagents and support
Exquisite sensitivity in bioluminescence
Full fluorescence tunability through the NIR spectrum
Compute Pure Spectrum spectral umixing for ultimate fluorescence sensitivity
Expandable system tailored to your workflow
Selected Publications
Lim et al (2021). Bioorthogonally surface‐edited extracellular vesicles based on metabolic glycoengineering for CD44‐mediated targeting of inflammatory diseases. J Extracellular Vesicles.https://doi.org/10.1002/jev2.12077
Lee et al (2020). NIR dye-loaded mesoporous silica nanoparticles for a multifunctional theranostic platform: Visualization of tumor and ischemic lesions, and performance of photothermal therapy. J Indus. Eng. Chem. 88:99-105. https://doi.org/10.1016/j.jiec.2020.03.027
Shim et al (2019). Carrier-free nanoparticles of cathepsin B-cleavable peptide-conjugated doxorubicin prodrug for cancer targeting therapy. Jrnl. Controlled Release. 294: 378-389. https://doi.org/10.1016/j.jconrel.2018.11.032
Lee et al (2019). Crushed Gold Shell Nanoparticles Labeled with Radioactive Iodine as a Theranostic Nanoplatform for Macrophage-Mediated Photothermal Therapy. Nano-Micro Letters. 11(36). https://doi.org/10.1007/s40820-019-0266-0
Zhang et al (2019). In vivo irreversible albumin-binding near-infrared dye conjugate as a naked-eye and fluorescence dual-mode imaging agent for lymph node tumor metastasis diagnosis. Biomaterials. 217:119279. https://doi.org/10.1016/j.biomaterials.2019.119279
Singh et al (2019). A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer. Clin Cancer Res. https://doi.org/10.1158/1078-0432.CCR-18-3007
Sonoda et al (2018). A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II. Mol Ther. 26(2): 1366-1374. https://doi.org/10.1016/j.ymthe.2018.02.032
He et al (2018). Repurposing disulfiram for cancer therapy via targeted nanotechnology through enhanced tumor mass penetration and disassembly. Acta Biomater. 28: 113-124. https://doi.org/10.1016/j.actbio.2017.12.023
Jung et al (2017). Hydrophobically modified polysaccharide-based on polysialic acid nanoparticles as carriers for anticancer drugs. Int. J Pharmaceutics. 520(1-2): 111-118. https://doi.org/10.1016/j.ijpharm.2017.01.055
Kafa et al (2016). Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood–brain barrier in vitro and in vivo. Jrnl. Controlled Release. 225: 217-229. https://doi.org/10.1016/j.jconrel.2016.01.031
For additional publications, please visit Google Scholar.
Cerenkov Emission from radioisotopes in tissue,Optical imaging detects photons in the visible range of the electromagnetic,spectrum. PET and SPECT imaging instruments are sensitive to photons in the much,higher energy range of x-rays and gamma rays. While the PET and SPECT probes,which can generate ...
Pre-clinical in vivo imaging application note on Bioimaging of Gene Delivery with In Vivo-jetPEI®. The delivery of nucleic acids into cells is essential for basic research as well as medical applications such as gene therapy. Viral vectors are efficient carriers, but their use is limited because of ...
With the potential to treat a wide range of disease, from organ damage to congenital defects, stem cell research and tissue engineering form the underlying basis of regenerative medicine. Significant advances in the science of skin regeneration, for example, have now made it possible to develop and ...
IVIS Lumina Series III Integrating Gold Standard Bioluminescence and Fluorescence In Vivo Technologies. The IVIS Lumina Series III from PerkinElmer provides an expandable, sensitive imaging system that is easy to use for both fluorescent and bioluminescent imaging in vivo. The Lumina Series III plat ...
Not only is it possible to load multiple images as a group, for example multiple days of a longitudinal study, but it is also possible to load multiple images and Overlay them i.e. bioluminescent tumor with fluorescent targeted drug acquired in two separate images.
Acquiring the most accurate quantitation of your bioluminescent sources requires a close understanding of the underlying kinetics involved in producing and capturing the detected light. After injection, the substrate for your bioluminescent probe will di
For many studies, it may be desirable to open a group of images together, for example, analyzing multiple days of longitudinal study side by side using the same scale.
Working with Image Math. Image Math is a rudimentary but effective method for Spectrum and Lumina users to subtract background from images without performing Spectral Unmixing.
