Iodoantipyrine, 4-[N-Methyl-¹⁴C]-, 50µCi (1.85MBq)

Iodoantipyrine readily crosses the blood-brain barrier, and has been used to measure total and regional cerebral blood flow in vivo.

References for NEC712:

1. ACW Huang, HC Lu, BC Shyu. Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain. JoVE (Journal of Visualized Experiments), 2016.
2. Asotra K., Ningaraj N., Black K.L. (2003) Measurement of Blood-Brain and Blood-Tumor Barrier Permeabilities with [14C]-Labeled Tracers. In: Nag S. (eds) The Blood-Brain Barrier. Methods in Molecular Medicine™, vol 89. Humana Press.
3. S Walenta, M Dellian, AE Goetz, GEH Kuhnle & W Mueller-Klieser. Pixel-to-pixel correlation between images of absolute ATP concentrations and blood flow in tumours. (1992) British Journal of Cancer 66, 1099–1102.