Inulin-carboxyl, labeled on carboxyl groups with C-14. Inulin-carboxyl-14C is commonly used in renal cearance studies.
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50 µCi quantities of [Carboxyl-14C]-Inulin-Carboxyl are available for your research. Application of [14C]Inulin can be found in: cerebrospinal fluid flow and penetration into brain following lateral ventricle and cisterna magna injections in rat, comparison of amniotic and intramembranous unidirectional permeabilities in late-gestation sheep, tyrosine phosphorylation of VE-cadherin and claudin-5 associated with TGF-ß1-induced permeability of centrally derived vascular endothelium, enhanced nasal absorption of hydrophilic markers after dosing with AT1002 (a tight junction modulator), etc. Special Information: The labeled inulin differs from the parent inulin in that the reducing group is replaced by a carboxyl group labeled with carbon-14. Approximately 25% of the inulin molecules contain a carboxyl group. Glomerular filtration studies (1) have indicated that the slight modification of the chain does not appreciably alter the physical properties of authentic inulin.
To solubilize inulin-carboxyl, [carboxyl-14C]-, it may be necessary to heat the material to 58°C. It has been found by gel permeation chromatography on Sephadex LH-20 that no hydrolysis or decomposition takes place when heating time is restricted to that necessary for dissolution.
| Detection Method | Radiometric |
|---|---|
| Fresh Lot Days | This product has a scheduled release date for the third Monday in July. |
| Label Position | Specifically Labeled |
| Product Brand Name | NEN Radiochemicals |
| Radioisotope | C-14 |
| Radionuclide | 14C |
| Shipping Condition | Ambient |
| Special Ordering Information | This is a radioactive product - shipping address must have a license to receive radioactive materials. |
| Unit Size | 50 µCi |
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This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.
This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.
