For research use only. Not for use in diagnostic procedures.
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Both fluorescence and bioluminescence are important imaging modalities for a variety of disease or biological models. Find out which reagents will work best for your application with a convenient collection of our most popular and most published fluorescent probes in sample size, as well as ready-to-use luciferin for bioluminescent imaging. Discover the broad utility of our reagents in a number of applications, including cancer, angiogenesis, arthritis, cardiovascular disease, and acute inflammation.
The availability of probes at 680 nm and 750 nm wavelengths further offers the opportunity for multiplex imaging of appropriate probe combinations to maximize information gained from research animals.
The In Vivo Fluorescent Agents Sample Pack includes the following five probes:
|Part Number||Fluorescent Probe||Biological Target|
|770504||XenoLight RediJect D-Luciferin**||Pre-formulated bioluminescent substrate ready for use in in vivo imaging with Firefly Luciferase|
|NEV10723EX||AngioSense 680EX*||Vascular probe:
Leaks into sites of edema/cancer
|NEV10878||IntegriSense 750*||αVβ3 integrin targeted probe:
Marker on tumors, neovasculature, and osteoclasts
|NEV10932||MMPSense 750 FAST*||Pan-MMP activatable probe:
Secreted marker of inflammatory cells, fibrosis, and tumor margins
|NEV10972EX||ProSense 750EX*||Pan-cathepsin activatable probe:
Lysosomal marker of inflammatory cells and tumor cells
*Sample size (each sample size vial contains 3 doses)
**Full size (RediJect D-Luciferin kit contains 10 vials, 5 doses per vial)
|Optical Imaging Classification||Bioluminescence imaging, Fluorescence Imaging|
|Quantity in a Package Amount||5.0 Units|
|Shipping Condition||Blue Ice|
|Unit Size||1 vial|
Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And our hard-earned expertise makes us a trusted provider of pre-clinical imaging solutions— with more than 9,000 peer reviewed articles as proof.
User guide for fluorescent imaging probes
The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick and efficient drug screening and evaluation. Read this White Paper to learn how preclinical in vivo imaging helps to ensure that smart choices are made by providing Go/No-Go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.