For research use only. Not for use in diagnostic procedures.
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PerkinElmer has developed a number of important fluorescence reagents that allow imaging of a variety of disease or biological models. Our most popular probes have been selected based on the important biomarkers they target. These probes, ProSense 680, AngioSense 680EX, FolateRSense 680, MMPSense 750 FAST, and IntegriSense 750, show broad utility in a number of applications, including cancer, angiogenesis, arthritis, cardiovascular disease, and acute inflammation. In addition, PerkinElmer’s VivoTag 680XL fluorophore provides a useful, in vivo-optimized fluorescent label for researchers to tag their own proteins, peptides, or antibodies as either imaging tools or for assessing protein/antibody biodistribution.
The availability of probes at 680 nm and 750 nm wavelengths further offers the opportunity for multiplex imaging of appropriate probe combinations to maximize information gained from research animals.
The Featured Probe Pack In Vivo Fluorescent Agents Panel includes the following six probes:
|Part Number||Fluorescent Probe||Biological Target|
|NEV10003||ProSense 680||Pan-cathepsin activatable probe:
Lysosomal marker of inflammatory cells and tumor cells
|NEV10054EX||AngioSense 680 EX||Vascular probe:
Leaks into sites of edema/cancer
|NEV10040||FolateRSense 680||Folate receptor targeted probe:
Marker on inflammatory cells; metabolic marker on tumor cells
|NEV10168||MMPSense 750 FAST||Pan-MMP activatable probe:
Secreted marker of inflammatory cells, fibrosis, and tumor margins
|NEV10873||IntegriSense 750||αVβ3 integrin targeted probe:
Marker on tumors, neovasculature, and osteoclasts
|NEV11118||VivoTag 680XL Protein Labeling Kit||NIR fluorescence labeling kit:
Labeling antibodies, proteins, and peptides for in vivo imaging
|Optical Imaging Classification||Fluorescence Imaging|
|Quantity in a Package Amount||6.0 Units|
|Shipping Condition||Blue Ice|
|Unit Size||1 vial|
User guide for fluorescent imaging probes