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Fluorescent Imaging Agent Panel – Featured Probes Pack

Get the flexibility you need with our Featured Probes In Vivo Agents Panel. This panel features a wide range of fluorescent probes specific to various disease areas as well as a fluorescent labeling kit to tag your own proteins, peptides or antibodies.

For research use only. Not for use in diagnostic procedures.

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NEV20011
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Overview

PerkinElmer has developed a number of important fluorescence reagents that allow imaging of a variety of disease or biological models. Our most popular probes have been selected based on the important biomarkers they target. These probes, ProSense 680, AngioSense 680EX, FolateRSense 680, MMPSense 750 FAST, and IntegriSense 750, show broad utility in a number of applications, including cancer, angiogenesis, arthritis, cardiovascular disease, and acute inflammation. In addition, PerkinElmer’s VivoTag 680XL fluorophore provides a useful, in vivo-optimized fluorescent label for researchers to tag their own proteins, peptides, or antibodies as either imaging tools or for assessing protein/antibody biodistribution.

The availability of probes at 680 nm and 750 nm wavelengths further offers the opportunity for multiplex imaging of appropriate probe combinations to maximize information gained from research animals.

 

The Featured Probe Pack In Vivo Fluorescent Agents Panel includes the following six probes:

Part Number Fluorescent Probe Biological Target
NEV10003 ProSense 680 Pan-cathepsin activatable probe:
Lysosomal marker of inflammatory cells and tumor cells
NEV10054EX AngioSense 680 EX Vascular probe:
Leaks into sites of edema/cancer
NEV10040 FolateRSense 680 Folate receptor targeted probe:
Marker on inflammatory cells; metabolic marker on tumor cells
NEV10168 MMPSense 750 FAST Pan-MMP activatable probe:
Secreted marker of inflammatory cells, fibrosis, and tumor margins
NEV10873 IntegriSense 750 αVβ3 integrin targeted probe:
Marker on tumors, neovasculature, and osteoclasts
NEV11118 VivoTag 680XL Protein Labeling Kit NIR fluorescence labeling kit:
Labeling antibodies, proteins, and peptides for in vivo imaging

Specifications

Optical Imaging Classification Fluorescence Imaging
Quantity in a Package Amount 6.0 Units
Shipping Condition Blue Ice
Unit Size 1 vial
Resources, Events & More
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Ebook

In Vivo Imaging Solutions eBook

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And our hard-earned expertise makes us a trusted provider of pre-clinical imaging solutions— with more than 9,000 peer reviewed articles as proof.

PDF 4 MB

Flyer

Fluorescent Panels Targeted for Your Research

Data sheet on PerkinElmer's Fluorescent Panels for In Vivo imaging

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User guide for fluorescent imaging probes

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The Role of In Vivo Imaging in Drug Discovery and Development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick and efficient drug screening and evaluation. Read this White Paper to learn how preclinical in vivo imaging helps to ensure that smart choices are made by providing Go/No-Go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.

PDF 748 KB