PerkinElmer
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Fluorescent Imaging Agent Panel – Arthritis

Detect molecular players in arthritis pathology with PerkinElmer’s In Vivo Arthritis Fluorescent Imaging Agent Panel.

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For research use only. Not for use in diagnostic procedures.

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NEV20003
2328.00 USD
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Detail Information

The biology of arthritis is complex, involving multiple cellular players, secreted factors, and processes that can lead to sever joint damage. Our fluorescent imaging probes targeting arthritis research allows in vivo imaging of the magnitude of inflammation, bone destruction, cartilage degradation, and vascular leak (edema) in a manner that non-invasively predicts the underlying histopathology of this disease.

The availability of probes at 680 nm and 750 nm wavelengths further offer the opportunity for multiplex imaging of appropriate probe combinations to maximize information gained from research animals.

 

The Arthritis In Vivo Fluorescent Agents Panel includes the following six probes:

Part Number Fluorescent Probe Biological Target
NEV10003 ProSense 680 Pan-cathepsin activatable probe:
Lysosomal marker of inflammatory cells
NEV10011EX AngioSense 750 EX Vascular probe:
Leaks into sites of edema
NEV10020EX OsteoSense 680 EX Bone turnover targeted probe:
Detects areas of exposed hydroxyapatite
NEV10126 MMPSense 680 Pan-MMP activatable probe:
Secreted marker of inflammatory cells, bone/cartilage degradation
NEV11000 CAT K 680 FAST Cathepsin K activatable probe:
Secreted marker of osteoclasts, bone degradation
NEV11098 CAT B 750 FAST Cathepsin B activatable probe:
Lysosomal marker of inflammatory cells

Specifications

Optical Imaging Classification Fluorescence Imaging
Quantity in a Package Amount 6.0 Units
Shipping Condition Blue Ice
Therapeutic Area Arthritis
Unit Size 1 vial