PerkinElmer
check quantity

ValiScreen Cells, opioid NOP (ORL1) receptor, human recombinant, HEK293

Stable, recombinant ValiScreen® cell line expressing the Opioid NOP (ORL1) receptor, human recombinant in HEK293 host cells.

Part Number RBHORLM-K
Buy Now

Please enter valid quantity

Please log in to add favorites.

NULL OR EMPTY CART

Cell Line Terms and Conditions must be accepted before orders are placed. Additional agreement needed for commercial use.

Overview

PerkinElmer’s ValiScreen® cell lines are provided in two vials of frozen cells, each containing ∽2.5 x 106 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available for each cell line.

Clonal selection for PerkinElmer’s ValiScreen cell lines is carried out with receptor binding. High and low expressors are then tested and selected for optimal binding and functional response according to the receptor specific transduction pathway.

PerkinElmer’s ValiScreen cell lines require accepted cell line Terms and Conditions prior to order processing. Additional agreement needed for commercial use. Contact us using the Request More Information button above for additional information regarding required documentation.

Specifications

Assay Target Class GPCR
Assay Validated Binding
Automation Compatible Yes
Host Cell HEK293
Product Brand Name ValiScreen
Receptor Type Opioid
Shipping Condition Dry Ice
Special Ordering Information Requires accepted Terms and Conditions. Additional agreement needed for commercial use.
Unit Size 5 million cells
Resources, Events & More
  • All

Application Note

AequoScreen aequorin-encoding Plasmids for performing aequorin luminescent assay starting from non-aequorin cell lines

Aequorin is a photo protein originating from the jellyfish Aequorea Victoria. The apo-enzyme (apoaequorin) is a 21 kD protein, which requires a hydrophobic prosthetic group, coelenterazine, to be converted to aequorin,the active form of the enzyme. This enzyme possesses 3 calcium binding sites which control its activity.

PDF 607 KB

Brochure

GPCRs: The Pathway to Discovery

G protein coupled-receptors (GPCRs) are one of the most intensively studied drug targets, with up to one-third of all marketed therapeutics acting by binding to GPCRs. Therapies that target GPCRs include both agonist and antagonists that are used in the treatment of disease in nearly every major organ system and hold significance in several therapeutic areas, such as cardiovascular diseases, neurosciences, respiratory diseases, metabolic disorders, oncology, and rare diseases.

We know the importance of furthering GPCR research - and we answer the call with application notes, white papers, and end-to-end solutions including reagents, instruments, and tools for all aspects of research into today’s most promising drug target.

PDF 1 MB
Take the Stress Out of Functional Testing - AequoZen and cAMPZen ready-to-use cells

PerkinElmer’s validated, ready-to-use AequoZen™or cAMPZen™ frozen, irradiated cells make it easier for you to perform functional testing of GPCRs. Just thaw and use! Reliable, convenient AequoZen cells for aequorin calcium testing or cAMPZen cells for cAMP testing let you get the testing done. So you can concentrate on results.

PDF 73 KB