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High-throughput AlphaLISA ELISA Alternative Screening Laboratory Automation Solution

This explorer G3 integrated HTS workstation is a fully automated,high-throughput system that incorporates AlphaLISA® technology, a novel, homogeneous, bead-based immunoassay to replace traditional ELISA assays in drug discovery, diagnostics and basic research.

Part Number EG31001
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For research use only. Not for use in diagnostic procedures.


Configuration Requirements:

  • Small footprint
  • Fully integrated system
  • Capacity to process 20 assay and 40 sample plates is 8 hours, including tip change
  • Ability to process plates in batches with each batch using a different protocol
  • Flexible liquid handling supporting use of single-use pipette tips

PerkinElmer’s AlphaLISA® technology is a novel, homogeneous, bead-based assay technology which can be used to replace traditional ELISA assays in drug discovery, diagnostics, and basic research. Because AlphaLISA assays are homogeneous, they can easily be automated. As an added value, AlphaLISA technology has been demonstrated to successfully work in high density formats (384-and 1536-well plates) enabling researchers to run high numbers of samples in small sample volumes.

Utilizing our proven explorer G3 integrated HTS workstation, we have designed a true single supplier, fully automated high-throughput AlphaLISA screening platform for use by a major pharmaceutical company. Sample transfer and standard addition are carried out by a PerkinElmer JANUS® automated liquid handling platform fitted with 96-tip pipetting head. Antibody solution and AlphaScreen® beads are dispensed by 2x PerkinElmer FlexDrop® IV dispensers. The two FlexDrop IV dispensers provide a total of eight independent dispense channels enabling the operator to run plates using different protocols within one run. Following incubation, plates are read on PerkinElmer’s EnVision® multimode reader.

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