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GSP® Neonatal GALT kit

The GSP® Neonatal GALT assay is used as an aid in screening newborns for classic galactosemia caused by GALT deficiency using the GSP instrument.

Part Number 3303-001U
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Galactosemia is an inherited disorder caused by a deficiency of one of three enzymes responsible for the metabolism of a-D-galactose.The most common form of the disease, classic galactosemia is caused by deficiency ofgalactose-1-phosphate uridyltransferase (GALT). Classic galactosemia affects from 1 in 30,000 to 1 in 60,000 live births. If not diagnosed and treated within the newborn period, it can lead to diarrhea, dehydration, jaundice, hepatic failure, hypoglycemia, cataracts, developmental retardation, and death within a few weeks. Treatment of the disease consists of withdrawal of all foods containing lactose and galactose from the diet.

GSP Neonatal GALT - the first automated GALT assay:

  • Faster assay - incubation time now only 2 h
  • Improved precision compared to manual assays
  • Provides results in today's preferred unit, U/dL
  • Contains reagents for 1152 tests (12 plates) clear microplates should be ordered separately in a bulk pack of 50.
  • Floating disks control

In the GSP Neonatal GALT assay, GALT in the blood sample catalyzes a reaction between galactose-1-phosphate and uridine diphosphoglucose contained in the assay substrate reagent. In the course of further reactions NADP (nicotinamide adenine dinucleotide phosphate) also contained in the assay substrate reagent is reduced to NADPH, a fluorescent substance that can be measured with excitation at 355 nm and emission detection at 460 nm.

All PerkinElmer neonatal products may not be available in all countries.


Assay Technology Enzymatic
Calibration Standards Yes
Detection Method Enzymatic
Disorders Galactosemia
Product Brand Name GSP®
Quantity in a Package Amount 1152.0 Units
Unit Size 1 Kit