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Epic PFP LB LC Columns - 250 mm, 4.6 mm I.D., 5 μm

The Epic PFP LB (low bleed) is a pentafluorophenyl that has been baseline stabilized and is ready for high performance separations. The Epic PFP LB is a truly unique stationary phase with properties significantly different than C18 phases. This unique characteristic results from bonded pentafluorophenyl groups imparting a π-π electron interaction which produces an enhanced retention for many compounds, such as natural products, halogenated compounds, aromatics, conjugated compounds and trace impurities in complex matrices. Many of these high-performance separations were not possible with existing PFP columns especially in the area of trace impurities where baseline bleed levels were unacceptable. Epic PFP LB columns have been stabilized to provide low column bleed, increased lifetimes, better pH stability, and superior LC-MS performance.

Part Number
Inner Diameter
Particle Size
List Price
Your Price
4.6 mm
5.0 µm
646.00 USD
20 mm
5.0 µm
3855.00 USD
30 mm
5.0 µm
6300.00 USD
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The Epic line our latest range of LC columns, based on high density monomerically bonded phases produced through a proprietary bonding process. Epic HPLC and UHPLC columns are compatible with a wide range of organic modifiers and buffers and stable over a wide pH range. All Epic products use an ultra-high purity metal free silica and undergo strict quality control testing. For flexibility, we offer a wide range of column sizes as well being fully scalable from analytical to preparative dimensions.

Features and Benefits:

  • Ultra-high purity silica for improved peak shape, especially for basic compounds
  • Extensive range of stationary phase chemistries with innovative bonding chemistry to enhance method development
  • High density bonding produces columns with better pH stability, increased sample loading and better lot-to-lot reproducibility
  • Extended pH stability across commonly used mobile phase buffers
  • Microbore to preparative dimensions available to allow flexibility and full scalability


Inner Diameter 4.6 mm
Length 250.0 mm
Particle Size 5.0 µm
Phase PFP LB
Resources, Events & More
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Application Brief

Rapid HPLC Analysis of Retinol Using an Epic C18 Column

Retinol is regularly used in the treatment and protection of skin. Once absorbed, it can induce the biosynthesis of collagen and reduce the expression of metalloprotease-. This application brief describes the use of an Epic C18 column coupled with the LC 300 liquid chromatograph ...

PDF 731 KB
Epic Polar HPLC Columns: Engineered for Polar Analytes

Epic Polar is a high density C18 packing specifically engineered for the retention of polar analytes such as small organic acids, water-soluble vitamins, cathecholamines and other polar compounds.

This product brief shows the retention characteristics of Epic Polar in the ...

PDF 477 KB
HPLC Assay of Risperidone Using an Epic C18 Column in Accordance With the United States Pharmacopeia

Risperidone is an antipsychotic medicine that works by changing the effects of chemicals in the brain. The methods for assessing Risperidone characteristics are described in the United States Pharmacopia and rely on chromatographic techniques.

In this application brief, we demonstrate the ...

PDF 465 KB

Product Note

Epic PFP-LB HPLC Columns

Epic PFP-LB is a truly unique stationary phase with properties significantly different than ODS phases. This unique characteristic results from bonded Pentafluorophenyl groups imparting a π-π electron interaction, producing an enhanced retention for many compounds.