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Epic FO LB LC Columns - 50 mm, 2.1 mm I.D., 1.8 μm

The Epic FO LB is a baseline stabilized alkyl perfluorinated C8 (perfluorooctyl), with low bleed characteristics and is well suited to the separation of trace impurities, especially for halogenated analytes, lipophilic compounds and environmental samples. Fluorinated phases are able to perform many unique and difficult separations which cannot be performed on the best available C18 columns. Traditionally, fluorinated phases have suffered from poor column lifetimes, unstable baselines and column bleed, especially when used with mass spectrometry (MS). Epic FO LB has been stabilized to provide low column bleed, increased lifetimes, better pH stability, and superior LC-MS performance.

Part Number
Inner Diameter
Particle Size
List Price
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512A91-EFO-LB
2.1 mm
1.8 µm
715.00 USD
 
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112191-EFO-LB
2.1 mm
3.0 µm
540.00 USD
 
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Overview

The Epic line our latest range of LC columns, based on high density monomerically bonded phases produced through a proprietary bonding process. Epic HPLC and UHPLC columns are compatible with a wide range of organic modifiers and buffers and stable over a wide pH range. All Epic products use an ultra-high purity metal free silica and undergo strict quality control testing. For flexibility, we offer a wide range of column sizes as well being fully scalable from analytical to preparative dimensions.

Features and Benefits:

  • Ultra-high purity silica for improved peak shape, especially for basic compounds
  • Extensive range of stationary phase chemistries with innovative bonding chemistry to enhance method development
  • High density bonding produces columns with better pH stability, increased sample loading and better lot-to-lot reproducibility
  • Extended pH stability across commonly used mobile phase buffers
  • Microbore to preparative dimensions available to allow flexibility and full scalability

Specifications

Inner Diameter 2.1 mm
Length 50.0 mm
Particle Size 1.8 µm
Phase FO LB
Resources, Events & More
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Application Brief

HPLC Analysis of Lamotrigine Related Compound B Impurity in Accordance with the USP Application Brief

Lamotrigine is an antiepileptic drug belonging in the phenyl triazine class. It is used in the treatment of both epilepsy and as a mood stabilizer for bipolar disorder. Lamotrigine related compound B also known as 2,3-dichlorobenzoic acid is a key intermediate for the antiepileptic drug Lamotrigine. It may be in found in the final product and needs to be monitored and controlled over the shelf life of the product.

The methods for assessing Lamotrigine related compound B are described in the United States Pharmacopeia1 and rely on chromatographic techniques. This application brief describes use of an Epic C18 column coupled with the LC 300 liquid chromatography system and SimplicityChrom chromatography data system (CDS).

PDF 407 KB

Brochure

HPLC and UHPLC Column Portfolio Interactive Brochure

Every decision you make in the lab affects your scientific outcomes – and that holds true for column choices. Sample solubility, chemical differences among analytes, and stationary phase chemistry are key factors in deciding which column is right for your application. The column vendor you choose must deliver the reliability, scalability, and reproducibility you need to get the most value from your method-development, quality-control, and preparative-purification processes.

Our innovative, highly efficient HPLC/UHPLC and supercritical fluid chromatography (SFC) column chemistries from ES Industries (now a PerkinElmer company) provide scientists like you with the highest quality columns, including novel chiral and achiral fluorinated phases specifically designed with pharmaceutical and environmental applications in mind. Building on ES Industries’ 40 years’ experience in column technology, we support you with applications assistance, method development guidance, and column recommendations, too.

PDF 862 KB