PerkinElmer
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XenoLight DiR Fluorescent Dye

XenoLight DiR NIR Fluorescent Dye can be used for non-invasive imaging of T-cell or stem cell homing in vivo

For laboratory use only. This product is intended for animal research only and not for use in humans.

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Overview

XenoLight DiR is a lipophilic, near infrared (NIR) fluorescent cyanine dye ideal for staining cytoplasmic membrane. The two long 18-carbon chains insert into the cell membrane, resulting in specific and stable cell staining with negligible dye transfer between cells. The near infrared property of this dye makes it ideal for in vivo imaging because of significantly reduced autofluorescence from the animal at higher wavelengths.

  • XenoLight DiR (DiIC18(7) or 1,1’-dioctadecyltetramethyl indotricarbocyanine Iodide)
  • Absorption/Emission: 748/780 nm
  • Ideal IVIS filter set: 710 ex/760 em

Specifications

Optical Imaging Classification Fluorescence Imaging
Product Brand Name XenoLight
Shipping Condition Blue Ice
Unit Size 25 mg
Wave Length 750 nm
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Brochure

XenoLight DiR - Track Cells In Vivo Non-Invasively

XenoLight DiR is a lipophilic, near infrared fluorescent cyanine dye ideal for staining the cytoplasmic membrane. The two long 18-carbon chains insert into the cell membrane, resulting in specific and stable cell staining with negligible dye transfer between cells.,XenoLight DiR in combination with PerkinElmer’s IVIS® imaging systems can be used for non-invasive imaging of cell homing (T cells, stem cells etc.) in vivo. The near infrared property of this dye makes it ideal for in vivo imaging because of significantly reduced auto-fluorescence from the animal at higher wavelengths.

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Data Sheet

Ebook

In Vivo Imaging Solutions eBook

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And our hard-earned expertise makes us a trusted provider of pre-clinical imaging solutions— with more than 9,000 peer reviewed articles as proof.

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Flyer

White Paper

The Role of In Vivo Imaging in Drug Discovery and Development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick and efficient drug screening and evaluation. Read this White Paper to learn how preclinical in vivo imaging helps to ensure that smart choices are made by providing Go/No-Go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.

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