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Dihydroalprenolol Hydrochloride, Levo-[Ring, Propyl-3H(N)]-, 1mCi (37MBq)

Dihydroalprenolol hydrochloride, tritiated on the ring propyl group. Dihydroalprenolol (DHA) is an alprenolol derivative that binds to beta-adrenergic receptors and acts as a beta-adrenergic blocker.

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250 µCi
1986.00 USD
1 mCi
7200.00 USD
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Dihydroalprenolol acts as an antagonist at beta adrenergic receptors. Beta blockers have been used to treat high blood pressure, heart arhythmia, and heart attack.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET720:

  1. Wolfgang Krawirtz, Erland Erdmann, Specific and unspecific binding of [3H](−)dihydroalprenolol to cardiac tissue, In Biochemical Pharmacology, Volume 28, Issue 8:1283-1288 (1979).
  2. Jir S. Tsai and A. Chen. Effect of L-triiodothyronine on (−)3H-dihydroalprenolol binding and cyclic AMP response to (−)adrenaline in cultured heart cells. Nature 275, 138–140 (1978).


Detection Method Radiometric
Label Position Nominally Labeled
Molecular Weight 287.8
Product Brand Name NEN Radiochemicals
Radioisotope H-3
Radionuclide 3H
Receptor Type Adrenoceptors
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area Cardiovascular, Inflammation, Diabetes, Metabolic Disorders, Gastrointestinal
Unit Size 1 mCi
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Radiometric Reagents Guide 2010-2011

For over 50 years PerkinElmer has been a leading supplier of radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. Today is no different. We have always been committed to providing you products for all of your radiometric needs and we are still committed t ...