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DAMGO, [Tyrosyl-3,5-3H(N)]-, 250µCi (9.25MBq)

DAMGO, tritiated at the tyrosyl 3,5 poisition. DAMGO is a synthetic opioid analog with high specificity for the μ-opioid receptor.

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250 µCi
2464.00 USD
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DAMGO is a synthetic agonist with high selectivity for the mu-opioid receptor (MOR). These receptors are a group of GPCRs that are involved in analgesia, and are potential drug targets for drug addiction.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET902:

  1. Page, K., Besret, L., Jain, M. et al. Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and µ-opioid receptor binding in the basal ganglia. Exp Brain Res (2000) 130: 142.
  2. Jessica R. Gugusheff, Sung Eun Bae, Alexandra Rao, Iain J. Clarke, Lucilla Poston, Paul D. Taylor, Clive W. Coen, Beverly S. Muhlhausler, Sex and age-dependent effects of a maternal junk food diet on the mu-opioid receptor in rat offspring, In Behavioural Brain Research (2016) 301: 124-131.


Concentration 1.0 - 10 mCi/mL
Detection Method Radiometric
Label Position Nominally Labeled
Molecular Weight 513.7
Product Brand Name NEN Radiochemicals
Radioisotope H-3
Radionuclide 3H
Receptor Type Opioid
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area CNS & Neurologic, Pain, Inflammation
Unit Size 250 µCi
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Radiometric Reagents Guide 2010-2011

For over 50 years PerkinElmer has been a leading supplier of radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. Today is no different. We have always been committed to providing you products for all of your radiometric needs and we are still committed t ...