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Bombesin (6-14), D-Tyr6[125I], 10µCi

Bombesin (6-14), labeled with 125I. Bombesin binds and activates bombesin receptors BBR1, BBR2, and BBR3, and is a tumor marker for lung cancer, gastric cancer, pancreative cancer, and neuroblastoma.

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10 µCi
1812.00 USD
25 µCi
3406.00 USD
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We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX377:

  1. Liu, J., Lao, Z.J., Zhang, J., Schaeffer, M.T., Jiang, M.M., Guan, X.M., Van der Ploeg, L.H., Fong, T.M. (2002), Molecular basis of the pharmacological difference between rat and human bombesin receptor subtype-3 (BRS-3). Biochemistry, 41 (28): 8954-8960.
  2. Yoshizaki, K., de Bock, V., Solomon, S. (1984), Origin of bombesin-like peptides in human fetal lung. Life Sci, 34 (9): 835-843.


Detection Method Radiometric
Fresh Lot Days First Monday of each month
Label Position Nominally Labeled
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Receptor Type Bombesin
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area CNS & Neurologic, Cancer
Unit Size 10 µCi
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Using the NENSure Packaging System from PerkinElmer

Since 1985, the unique NENSure system has set the standard for radiochemical packaging. Based on proven performance over millions of shipments, the system provides: Ease of use, Safe storage of unused product and Reduced radiation exposure. Many NEN brand research products, including 32P-, 33P-, 35 ...

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