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N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.

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Unit Size
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NEX120250UC
250 µCi
864.00 USD
 
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NEX120001MC
1 mCi
1438.00 USD
 
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NEX120002MC
2 mCi
2313.00 USD
 
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Overview

Iodination of proteins is a common method of adding a tracer with high specific activity to your protein of interest. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative methods. Bolton-Hunter reagent can be used to label peptides and proteins containing lysine residues.

Specifications

Concentration 1.0 - 10 mCi/mL
Detection Method Radiometric
Fresh Lot Days First Monday
Label Position Nominally Labeled
Molecular Weight 387.2
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Shipping Condition Ambient
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Unit Size 250 µCi
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