Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.
true falseIodination of proteins is a common method of adding a tracer with high specific activity to your protein of interest. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative methods. Bolton-Hunter reagent can be used to label peptides and proteins containing lysine residues.
| Concentration | 1.0 - 10 mCi/mL |
|---|---|
| Detection Method | Radiometric |
| Fresh Lot Days | First Monday |
| Label Position | Nominally Labeled |
| Molecular Weight | 387.2 |
| Product Brand Name | NEN Radiolabeled Ligands |
| Radioisotope | I-125 |
| Radionuclide | 125I |
| Shipping Condition | Ambient |
| Special Ordering Information | This is a radioactive product - shipping address must have a license to receive radioactive materials. |
| Unit Size | 250 µCi |
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