The DELFIA® and AutoDELFIA™ Free hCGß Kits are for the quantitative determination of the free beta subunit of human Chorionic Gonadotrophin (Free hCGß) in maternal serum.
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Typically, the level of the free hCGß subunit is significantly increased in maternal serum during both the first and the second trimesters of pregnancy if the fetus is affected by Down´s syndrome. These solid phase, two-site fluoroimmunometric assays are based on the direct sandwich technique in which two monoclonal antibodies are directed against two separate antigenic determinants on the free hCGß molecule.
Analytical sensitivity is typically better than 0.2 ng/mL.
| Assay Technology | DELFIA |
|---|---|
| Detection Method | Time-Resolved Fluorescence (TRF) |
| Disorders | Down Syndrome |
| Product Brand Name | AutoDELFIA® |
| Research Areas | Maternal & Fetal Health |
