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Angiotensin II (human), [125I]-Tyr4, 10 μCi

Angiotensin II (human), labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin II binds and activates angiotensin II receptor type 1 (AT1) and type 2 (AT2) receptors, a class of GPCRs important in vasoconstriction. Angiotensin II is a potential drug target for blood pressure regulation.

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10 µCi
1509.00 USD
50 µCi
5300.00 USD
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We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX105:

  1. Oppermann, M., Gess, B., Schweda, F., and Castrop, H. (2009), Atrap Deficiency Increases Arterial Blood Pressure and Plasma Volume. JASN, 21 (3): 468-477.


Detection Method Radiometric
Product Brand Name NEN Radiochemicals
Radioisotope 125I
Shipping Condition Ambient
Unit Size 10 µCi