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Streptavidin AlphaPlex™ 645 (Sm) Acceptor Beads, 5 mg

The Streptavidin coated AlphaPlex™ 645 (Samarium) Acceptor beads are used to capture a wide variety of biotinylated reagents, ranging from small nucleotides to very large proteins. To avoid steric hindrance, it is recommended to use biotin derivatives including an aliphatic spacer composed of at least six carbons.

For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Part Number
Unit Size
List Price
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AP125SM-C
250 µg
824.00 USD
 
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AP125SM-M
5 mg
8400.00 USD
 
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AP125SM-R
25 mg
33800.00 USD
 
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Overview

The Streptavidin coated AlphaPlex™ 645 (Samarium) Acceptor beads are used to capture a wide variety of biotinylated reagents, ranging from small nucleotides to very large proteins. To avoid steric hindrance, it is recommended to use biotin derivatives including an aliphatic spacer composed of at least six carbons. These beads can be used in conjunction with Alpha Donor beads to create no-wash assays for:


  • Protein-protein interactions
  • Protein-DNA interactions
  • Protein-RNA interactions
  • Protein-small molecule interactions
  • Analyte detection
  • Biomarker detection
  • Antibody detection
  • Enzymatic assays
  • Other immunoassays

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AlphaPlex Acceptor beads are intended to be used in multiplexing assays, in conjunction with AlphaLISA Acceptor beads and Alpha Donor beads. In a typical Alpha assay, 1 mg of Acceptor beads is sufficient to run 1,000-2,000 wells using a 50 μL reaction volume.

Specifications

Antibody Conjugates Streptavidin
Automation Compatible Yes
Bead Type or Core Bead Type AlphaPlex Samarium (645) Acceptor
Detection Method Alpha
Experimental Type In vitro
Format Microplates
Product Brand Name AlphaPlex
Quantity in a Package Amount 1.0 per pack
Shipping Condition Blue Ice
Unit Size 5 mg
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Application Note

Development of Pharmacokinetic (PK) Assays for Detecting Biosimilars Targeting TNF alpha using AlphaLISA

Anti-inflammatory monoclonal antibody drugs that specifically target TNFα, such as Humira®, have been highly successful in the market. As patents expire on these top-selling drugs, effort has been placed on developing biosimilars. Biosimilars differ from small molecule generi ...

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