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Yes-associated protein 1 (YAP) is a protein that is a transcriptional regulator which activates the transcription of genes involved in cell proliferation and suppresses apoptotic genes. YAP is a critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression. YAP is a potent oncogene and is amplified in numerous human cancers.
The AlphaLISA SureFire Ultra Human and Mouse Phospho-YAP (Ser127) assay is a sandwich immunoassay for the quantitative detection of phospho-YAP (Ser127) in cellular lysates, using Alpha Technology.
|Experimental Type||In vitro|
|Product Brand Name||AlphaLISA SureFire Ultra|
|Shipping Condition||Blue Ice|
|Target Species||Human, Mouse|
|Unit Size||500 Assay Points|
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...