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AlphaLISA SureFire Ultra Human Phospho-TDP-43 (Ser409/410) Detection Kit, HV

The AlphaLISA® SureFire® Ultra Human Phospho-TDP-43 (Ser409/410) assay is a sandwich immunoassay for quantitative detection of phospho-TDP-43 (Ser409/410) in cellular lysates using Alpha Technology.

For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Part Number
Unit Size
List Price
Your Price
Quantity
ALSU-PTDP43-A500
500 Assay Points
2216.00 USD
 
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ALSU-PTDP43-A10K
10,000 Assay Points
13500.00 USD
 
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ALSU-PTDP43-A50K
50,000 Assay Points
43500.00 USD
 
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ALSU-PTDP43-A-HV
100 Assay Points
660.00 USD
 
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Overview

TAR DNA binding protein 43 (TDP-43) is a nucleic acid binding protein involved in RNA-related metabolism. In pathological conditions (mutation or deregulation), TDP-43 forms insoluble inclusion bodies in the cytoplasm of neurons in the brain and spinal cord. Aggregated TDP-43 has been identified as a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD), and more widely in several neurodegenerative diseases such as Alzheimer’s disease.

The AlphaLISA SureFire Ultra Human Phospho-TDP-43 (Ser409/410) is a sandwich immunoassay for the quantitative detection of phospho-TDP-43 (Ser409/410) in cellular lysates, using Alpha Technology.

Formats:

  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with:

  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies

Alpha SureFire kits can be used for:

  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Assay Points (200-50,000) 100 Assay Points
Assay Target TDP-43
Assay Technology Alpha
Automation Compatible Yes
Detection Method Alpha
Experimental Type In vitro
Product Brand Name AlphaLISA SureFire Ultra
Shipping Condition Blue Ice
Target Species Human
Therapeutic Area Neuroscience
Unit Size 100 Assay Points
Resources, Events & More
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Application Brief

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Brochure

Alpha Technology Solutions

Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.

PDF 2 MB
Drug Discovery Screening Solutions Brochure

Find out about our range of integrated solutions for drug discovery screening in this e-brochure.

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PDF 4 MB