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Polo-like kinase 1 (PLK1) is a Ser/Thr kinase essential for cell division (mitosis) and as such, a key regulator of the G2/M checkpoint of the cell cycle. PLK1 is activated by phosphorylation of Thr210 by AurA kinase and active PLK1 phosphorylates CDC25. Overexpression of PLK1 is associated with many types of cancers, including lung, breast, liver, and osteosarcoma.
The AlphaLISA SureFire Ultra Human and Mouse Total PLK1 is a sandwich immunoassay for the quantitative detection of total PLK1 in cellular lysates, using Alpha Technology.
|Assay Points (200-50,000)||100 Assay Points|
|Experimental Type||In vitro|
|Product Brand Name||AlphaLISA SureFire Ultra|
|Shipping Condition||Blue Ice|
|Target Species||Human, Mouse|
|Therapeutic Area||Neuroscience, Oncology|
|Unit Size||100 Assay Points|
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...