For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Please enter valid quantity
Please log in to add favorites.
NULL OR EMPTY CART
Pyruvate dehydrogenase E1 subunit alpha 1 (PDHA1) is an enzyme involved in the pyruvate dehydrogenase complex (PDC). PDC is a multi-enzyme complex of the mitochondria that provides a link between glycolysis and the Krebs cycle and plays an essential role in producing acetyl-CoA from glucose leading to ATP or energy production. The PDHA1 enzyme is regulated by phosphorylation and dephosphorylation. Diseases associated with PDHA1 include pyruvate dehydrogenase E1-alpha deficiency, X-linked Leigh syndrome, and numerous solid tumor cancers.
The AlphaLISA SureFire Ultra Human and Mouse Total PDHA1 Detection Kit is a sandwich immunoassay for the quantitative detection of total PDHA1 in cellular lysates, using Alpha Technology.
|Assay Points (200-50,000)||50000 Assay Points|
|Experimental Type||In vitro|
|Product Brand Name||AlphaLISA SureFire Ultra|
|Shipping Condition||Blue Ice|
|Target Species||Human, Mouse|
|Unit Size||50,000 Assay Points|
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater assay throughput and sensitivity has evolved. In response, more robust immunoassays have been developed to address some of the limitations of the standard, colorimetric ELISA.
Find out about the most common limitations of traditional ELISAs and how different ELISA alternative technologies address these limitations.
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automated liquid handling, assays and reagents, imaging and detection systems, and informatics.
Working independently or together, with our solutions you can achieve consistent and accurate results. By accelerating the identification and characterization of effective and safe drug candidates, the PerkinElmer portfolio enables you to optimize efficiency in your lab and deliver more actionable, real-world results.
Download the brochure to learn more about how we can partner with you so that you can discover smarter, more effective, data-driven breakthroughs in the critical screening stages of drug discovery and development.