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Lymphocyte cytosolic protein 2 (SLP76) is a signal-transducing adaptor protein encoded by LCP2. This protein acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. Activated SLP76 translocates to the plasma membrane and promotes a multi-protein complex which participates in the activation, survival, and proliferation of T-Lymphocytes. SLP76 is associated with numerous therapeutic areas, including diseases such as multiple sclerosis, rheumatoid arthritis, psoriasis, and cancer.
The AlphaLISA SureFire Ultra Human and Mouse Phospho-SLP76 (Ser376) assay is a sandwich immunoassay for the quantitative detection of phospho-SLP76 (Ser376) in cellular lysates, using Alpha Technology.
|Experimental Type||In vitro|
|Product Brand Name||AlphaLISA SureFire Ultra|
|Shipping Condition||Blue Ice|
|Target Species||Human, Mouse|
|Therapeutic Area||Autoimmunity, Oncology, Immuno-oncology|
|Unit Size||100 Assay Points|
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...