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AlphaLISA SureFire Ultra Mouse Phospho-PERK (Thr980) Detection Kit, 10,000 Assay Points

The AlphaLISA® SureFire® Ultra Mouse Phospho-PERK (Thr980) assay is a sandwich immunoassay for quantitative detection of phospho-PERK (Thr980) in cellular lysates using Alpha Technology.

For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Part Number
Unit Size
List Price
Your Price
Quantity
ALSU-PPERK-A500
500 Assay Points
1648.00 USD
 
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ALSU-PPERK-A10K
10,000 Assay Points
10200.00 USD
 
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ALSU-PPERK-A50K
50,000 Assay Points
29000.00 USD
 
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ALSU-PPERK-A-HV
100 Assay Points
571.00 USD
 
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Overview

Protein kinase-like endoplasmic reticulum kinase (PERK) is an eIF2α kinase and transmembrane protein that resides in the endoplasmic reticulum (ER) membrane and is activated upon ER stress signals. PERK activation during ER stress correlates with autophosphorylation of its cytoplasmic kinase domain. Phosphorylation of PERK at Thr980 serves as a marker for its activation status. PERK promotes tumor growth by limiting oxidative DNA damage and is associated with neurodegenerative diseases and many cancers.

The AlphaLISA SureFire Mouse Phospho-PERK (Thr980) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-PERK (Thr980) in cellular lysates, using Alpha Technology.

Formats

  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with

  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies

Alpha SureFire kits can be used for

  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Assay Points (200-50,000) 10000 Assay Points
Assay Target PERK
Assay Technology Alpha
Automation Compatible Yes
Detection Method Alpha
Experimental Type In vitro
Product Brand Name AlphaLISA SureFire Ultra
Shipping Condition Blue Ice
Target Species Mouse
Therapeutic Area Neuroscience, Oncology
Unit Size 10,000 Assay Points
Resources, Events & More
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Application Brief

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Brochure

Alpha Technology Solutions

Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.

PDF 2 MB
Drug Discovery Screening Solutions Brochure

Find out about our range of integrated solutions for drug discovery screening in this e-brochure.

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