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Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) is a critical regulator of programmed necroptosis, an inflammatory form of cell death with important functions in pathogen-induced and sterile inflammation. RIP3 mediates necroptosis in conjunction with RIPK1 and MLKL. Due to the inflammation caused by necroptosis, RIPK3 is associated with a variety of inflammatory diseases.
The AlphaLISA SureFire Ultra Human Phospho-RIP3 (Ser227) assay is a sandwich immunoassay for the quantitative detection of phospho-RIP3 (Ser227) in cellular lysates, using Alpha Technology.
|Experimental Type||In vitro|
|Product Brand Name||AlphaLISA SureFire Ultra|
|Shipping Condition||Blue Ice|
|Therapeutic Area||Autoimmunity, Central Nervous System, Neuroinflammation|
|Unit Size||10,000 Assay Points|
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...