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AlphaLISA SureFire Ultra Human Total ERα Detection Kit, HV

The AlphaLISA® SureFire® Ultra Human Total Estrogen Receptor α (ERα) assay is a sandwich immunoassay for quantitative detection of total ERα in cellular lysates using Alpha Technology.

For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Part Number
Unit Size
List Price
Your Price
Quantity
ALSU-TERA-A500
500 Assay Points
2216.00 USD
 
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ALSU-TERA-A10K
10,000 Assay Points
13500.00 USD
 
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ALSU-TERA-A50K
50,000 Assay Points
43500.00 USD
 
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ALSU-TERA-A-HV
100 Assay Points
660.00 USD
 
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Overview

Estrogen Receptors (ERs) are a group of proteins found inside cells and exist in two classes: ERα and ERβ. ERs are activated by estrogen and are able to translocate into the nucleus and bind to DNA to regulate the activity of different genes, but also have functions independent of DNA binding. ERs are expressed in >70% of all breast cancers with ERα being the main target in clinical approaches for controlling hormonally responsible breast cancer. ERα is associated with a variety of other cancers, including prostate, liver, and pancreatic ductal adenocarcinoma.

The AlphaLISA SureFire Ultra Human Total ERα Detection Kit is a sandwich immunoassay for the quantitative detection of total ERα in cellular lysates, using Alpha Technology.

Formats:

  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with:

  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies

Alpha SureFire kits can be used for:

  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Assay Points (200-50,000) 100 Assay Points
Assay Target ERα
Assay Technology Alpha
Automation Compatible Yes
Detection Method Alpha
Experimental Type In vitro
Product Brand Name AlphaLISA SureFire Ultra
Shipping Condition Blue Ice
Target Species Human
Therapeutic Area Oncology
Unit Size 100 Assay Points
Resources, Events & More
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Application Brief

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The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...

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Brochure

Alpha Technology Solutions

Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.

PDF 2 MB
Drug Discovery Screening Solutions Brochure

Find out about our range of integrated solutions for drug discovery screening in this e-brochure.

Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...

PDF 4 MB