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Estrogen Receptors (ERs) are a group of proteins found inside cells and exist in two classes: ERα and ERβ. ERs are activated by estrogen and are able to translocate into the nucleus and bind to DNA to regulate the activity of different genes, but also have functions independent of DNA binding. ERs are expressed in >70% of all breast cancers with ERα being the main target in clinical approaches for controlling hormonally responsible breast cancer. ERα is associated with a variety of other cancers, including prostate, liver, and pancreatic ductal adenocarcinoma.
The AlphaLISA SureFire Ultra Human Phospho-ERα (Ser118) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-ERα (Ser118) in cellular lysates, using Alpha Technology.
|Assay Points (200-50,000)||10000 Assay Points|
|Experimental Type||In vitro|
|Product Brand Name||AlphaLISA SureFire Ultra|
|Shipping Condition||Blue Ice|
|Unit Size||10,000 Assay Points|
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...