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AlphaLISA SureFire Ultra Human Phospho-Cyclin D1 (Thr286) Detection Kit, 10,000 Assay Points

The AlphaLISA® SureFire® Ultra Human Phospho-Cyclin D1 (Thr286) assay is a sandwich immunoassay for quantitative detection of phospho-cyclin D1 (Thr286) in cellular lysates using Alpha Technology.

For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Part Number
Unit Size
List Price
Your Price
Quantity
ALSU-PCYCD1-A500
500 Assay Points
1648.00 USD
 
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ALSU-PCYCD1-A10K
10,000 Assay Points
10200.00 USD
 
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ALSU-PCYCD1-A50K
50,000 Assay Points
29000.00 USD
 
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ALSU-PCYCD1-A-HV
100 Assay Points
571.00 USD
 
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Overview

Cyclin D1 is encoded by CCND1 and is a member of the highly conserved cyclin family, which includes Cyclin D2 and Cyclin D3. Cyclin family members are important regulators of cell cycle progression and act as mediatiors of growth factor dependent G1 to S phase progression by playing the role of allosteric regulators of CDK4/6. Cyclin D1 is an oncogene and is found to be overexpressed in many human cancers. Abnormal levels of Cyclin D1 result in dysregulated CDK4/6 activity and leads to tumorigenesis.

The AlphaLISA SureFire Human Phospho-Cyclin D1 (Thr286) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-Cyclin D1 (Thr286) in cellular lysates, using Alpha Technology.

Formats

  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with

  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies

Alpha SureFire kits can be used for

  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Assay Points (200-50,000) 10000 Assay Points
Assay Target Cyclin D1
Assay Technology Alpha
Automation Compatible Yes
Detection Method Alpha
Experimental Type In vitro
Product Brand Name AlphaLISA SureFire Ultra
Shipping Condition Blue Ice
Target Species Human
Therapeutic Area Oncology
Unit Size 10,000 Assay Points
Resources, Events & More
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Application Brief

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Brochure

Alpha Technology Solutions

Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.

PDF 2 MB
Drug Discovery Screening Solutions Brochure

Find out about our range of integrated solutions for drug discovery screening in this e-brochure.

Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...

PDF 4 MB