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Mammalian oncogenic transcription factor c-Myb is a member of the MYB family of proteins, encoded by the C-MYB gene, which is located in chromosome 6. The family received its name because of its association with myeloblastosis, taking the letters ‘m’, ‘y’ and ‘b’ from this word to create the family name. C-myb controls several genes related to cell proliferation, differentiation, and apoptosis. Sustained and high levels of MYB expression are seen in leukemia, colon cancer, breast cancer, and adenoid cystic carcinoma.
The AlphaLISA SureFire Ultra Human Phospho-c-Myb (Ser11) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-c-Myb (Ser11) in cellular lysates, using Alpha Technology.
|Assay Points (200-50,000)||100 Assay Points|
|Experimental Type||In vitro|
|Product Brand Name||AlphaLISA SureFire Ultra|
|Shipping Condition||Blue Ice|
|Unit Size||100 Assay Points|
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater assay throughput and sensitivity has evolved. In response, more robust immunoassays have been developed to address some of the limitations of the standard, colorimetric ELISA.
Find out about the most common limitations of traditional ELISAs and how different ELISA alternative technologies address these limitations.
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automated liquid handling, assays and reagents, imaging and detection systems, and informatics.
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Download the brochure to learn more about how we can partner with you so that you can discover smarter, more effective, data-driven breakthroughs in the critical screening stages of drug discovery and development.