PerkinElmer
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AequoZen frozen cells Starter Kit

AequoZen cells expressing the histamine H1 or the muscarinic M5 receptor for flash-luminescence assay.

This kit contains living cells. Some AequoZen™ FroZen Cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information.

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ES-001-AF
2239.00 USD
 
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Overview

AequoZen cells expressing the histamine H1 or the muscarinic M5 receptor for flash-luminescence assay. Recombinant, in CHO-K1 host cell. The kit contains two vials of cryopreserved H1 cells (strong calcium response) and four vials of cryopreserved M5 cells (weaker calcium response). A detailed user manual includes protocols and pharmacological properties of each recombinant receptor enabling you to become familiar with the AequoScreen technology. Please inquire at your local sales office for more information. You are authorized to utilize these frozen cell preparations one time only. Any attempt to transfer, re-use, or propagate these cells is expressly unauthorized and a violation of the product terms and conditions of sale.

Specifications

Assay Target Type Cell line
Assay Validated Calcium Luminescence
Host CHO-K1
Product Brand Name AequoZen
Second Messenger Release Calcium flux
Shipping Condition Dry Ice
Therapeutic Area Central Nervous System, Pain, Cardiovascular, Inflammation, Gastrointestinal
Unit Size 1 kit
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Application Note

AequoScreen aequorin-encoding Plasmids for performing aequorin luminescent assay starting from non-aequorin cell lines

Aequorin is a photo protein originating from the jellyfish Aequorea Victoria. The apo-enzyme (apoaequorin) is a 21 kD protein, which requires a hydrophobic prosthetic group, coelenterazine, to be converted to aequorin,the active form of the enzyme. This enzyme possesses 3 calcium binding sites which ...

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Brochure

GPCRs: The Pathway to Discovery

G protein coupled-receptors (GPCRs) are one of the most intensively studied drug targets, with up to one-third of all marketed therapeutics acting by binding to GPCRs. Therapies that target GPCRs include both agonist and antagonists that are used in the treatment of disease in nearly every major ...

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Manual

AequoZen Frozen Cells Starter Kit

G protein coupled receptors (GPCRs) have been considered as a highly “druggable” target for many years, with over 40% of marketed drugs acting to modulate their function. For many years, radiometric techniques have dominated GPCR screening. However in the last decade the development of functional as ...

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