The Protein Clear™ HR LabChip is designed for the LabChip® GXII Touch microfluidic capillary electrophoresis (CE-SDS) system. This chip works with the Protein Clear HR Reagent Kit (Part Number: CLS960014 sold separately). This chip is available in a single pack.
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For research use only. Not for use in diagnostic procedures.
The Protein Clear HR assay is designed for the high-resolution protein purity assessment of monoclonal antibodies (mAbs) within research and development, enabling the detection and visualization of impurities within a sample, down to 5 ng/µL. Combined with the analytical power and speed of the LabChip® GXII Touch™ system and IntelliChip™ assay optimization technology, accelerate your protein development workflows with unmatched throughput and reproducibility.
System Requirements: The Protein Clear HR assay requires a LabChip GXII Touch instrument with V1.6 software or newer and Data Reviewer V5.4 or newer.
| Model Compatible With | LabChip GXII Touch 24 |
|---|---|
| Product Brand Name | LabChip GXII |
| Research Areas | Drug Discovery & Manufacturing, Drug Development & Manufacturing, Food & Agriculture |
| Sample Type | Protein |
| Unit Size | 1 |
| Protein Clear HR Assay Specifications | |
|---|---|
| Parameter | Specification |
| Sizing Range | 14-250 kDa |
| Maximum Sample Concentration | 2000 ng/μL |
| Sizing Resolution* | Resolution > 1.0 for VeriMAb reference standard |
| Sizing Precision RSD (CV) | <2% |
| Relative Migration time Precision RSD (CV) | <2% |
| Percent Purity Reproducibility | <0.5% Main Non Reduced IgG <5% all other peaks |
| Sensitivity (LOD) | 5 ng/μL (mAb, non-reduced main peak) |
| Linear Concentration Range | 10 – 1000 ng/ μL (mAb, non-reduced main peak) |
| Linearity (R^2) | >0.995 |
| Separation Time per sample | 65 seconds |
| Maximum number of samples per calibration | 96 |
| Chip Lifetime | 400 samples |
| Reagent Kit Primes | 10 |
| Minimum sample volume | 2 μL |
