125I Radioiodination Services

Outsource your Iodination with confidence. From your initial inquiry, through scientific consultation, radiolabeling, purification, packaging and shipment you can trust the attentiveness of PerkinElmer’s Custom Iodination Team to diligently manage the 125I radioabeling of your proprietary molecule.

From the start, you will have direct access to PerkinElmer’s 60 years of experience in radiochemistry. Our collaborative team will confidentially advise you on the appropriate 125I labeling technique that best maintains the functional structure, biological activity and radiochemical stability of your unique molecule. Retaining the molecule's integrity is essential for the success of Radiometric Assays such as:

• Pharmacokinetic/Pharmacodynamic (PK/PD)
• Receptor Ligand Binding
• Quantitative Whole Body Autoradiography (QWBA)
• Radioimmunoassay (RIA)

Once your precious molecule is in our hands, expect a high yield and quick turnaround. To keep you on pace, your molecule will be efficiently Iodinated, purified and packaged with the appropriate buffer then shipped back to you in a secure container within a week. Trust PerkinElmer’s proficiency in logistics and management of radiolabeling services.

Available Radioiodination Services:

• Bolton-Hunter Reagent – peptides or proteins containing lysine residues
• Chloramine-T - peptides and proteins naturally containing, or chemically modified to introduce either tyrosine or histidine
• Iodogen® - peptides or proteins containing tyrosine or histidine side chain rings
• Lactoperoxidase -peptides and proteins naturally containing or chemically modified to contain tyrosine
• Custom Labeling Methods – we will review proposals for Iodination specific to your unique compound