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IVISense 2-DG 750 Fluorescent Probe in RediJect Solution (4 vials) (XenoLight)

IVISense 2-DeoxyGlucosone (DG) (XenoLight 2-DG) fluorescent imaging probes in RediJect Solution enable in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, these probes have been designed to contain four 2-DG molecules per dye molecule.

IVISense 2-DG probes are available in either 1 or 4 vial quantities and come in a convenient, ready-to-use injectable format.

For research use only. Not for use in diagnostic procedures.

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Overview

IVISense 2-DG 750 Fluorescent Probe - RediJect Solution (4 vials):

  • Novel ready-to-use probe to monitor glucose uptake in vivo non-invasively
  • Dispensed to image 20 mice (based on 30g/mouse)
  • Maximum glucose targeting and enhanced tumor uptake
  • in vivo imaging quality, validated on our industry leading IVIS® optical imaging systems

Specifications

Fluorescent Agent Type Targeted
Optical Imaging Classification Fluorescence Imaging
Product Brand Name IVISense
Quantity in a Package Amount 20.0 Units
Shipping Condition Blue Ice
Therapeutic Area Arthritis, Inflammation, Oncology/Cancer
Unit Size 1 Kit (20 animals)
Wave Length 750 nm
Resources, Events & More
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Ebook

In Vivo Imaging Solutions eBook

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And our hard-earned expertise makes us a trusted provider of pre-clinical imaging solutions— with more than 9,000 peer reviewed articles as proof.

PDF 4 MB

Flyer

Best Practices for Designing An Effective In Vivo Fluorescence Imaging Study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into disease processes and treatment effects. Designing an effective study from the beginning can help save time and resources.

Learn about several important best practices, from proper probe selection to study design to imaging technique tips and tricks needed to generate meaningful biological information from your in vivo fluorescence imaging studies.

PDF 507 KB
XenoLight RediJect 2-DG-750 Probe (Product Sheet)

XenoLight RediJect 2-DeoxyGlucosone (DG)-750 is a fluorescent,probe for in vivo targeting of tumors that typically exhibit elevated,glucose uptake rate in comparison to surrounding tissues. To achieve,maximum glucose targeting and enhanced tumor uptake, the probe,has been designed to contain four 2-DG molecules per dye molecule.,As indicated in Figure 1, RediJect 2-DG-750 probe showed specific,accumulation to LL-2 tumors shortly after delivery. In addition, specific,tumor labeling with the RediJect 2-DG-750 probe has also been,demonstrated with Breast (MDA-MB-231) Prostate (PC-3M) and Lung,(NCI-H460) tumors, further validating the utility of this probe as a generic fluorescence reagent for in vivo tumor targeting.

PDF 985 KB

White Paper

The Role of In Vivo Imaging in Drug Discovery and Development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick and efficient drug screening and evaluation. Read this White Paper to learn how preclinical in vivo imaging helps to ensure that smart choices are made by providing Go/No-Go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.

PDF 547 KB