In Vivo Imaging of Drug-Induced Liver Injury Using NIR Fluorescent Imaging Agents


Drug induced liver injury (DILI) is a major reason for late stage termination of drug discovery research projects, and a s result, assessment is being integrated earlier in the drug development process. In vivo optical imaging offers non-invasive detection of a variety of biological changes associated with disease and treatment in preclinical animal models and this approach is ideal for in vivo toxicology determination early in the development process. Watch this webinar, presented by Dr. Jeffrey Peterson, Director of Applied Biology at PerkinElmer, to learn how near infrared (NIR) imaging techniques were used for detection and quantification of liver toxicity in living mice, using a variety of NIR fluorescent imaging agents.