Introduction
Traditional Chinese medicine (TCM) and other alternative medicines have a rich history of healing and have been practiced for thousands of years. These treatments rely on analytical testing methods to meet pharmacopoeia standards such as Chinese Pharmacopoeia (ChP) and new, 2020 ChP standards. Due to the chemical diversity of TCM ingredients and finished products, chromatographic techniques are important to the analytical methods needed to meet ChP standards. Here, we’ve collected widely used TCM workflows utilizing the PerkinElmer LC 300 UHPLC system, SimplicityChrom™ software, PerkinElmer Epic™ columns, and a variety of chromatography consumables which enable the safety and quality ingredients in TCM products.
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Characteristic Components Analysis in Lonicerae Japonica Flos
Lonicera Japonica Flos is a common TCM for treating inflammation and infection disease. This method supports the quality control efforts in the analysis of seven components in Lonicera Japonica Flos samples.
Chlorogenic Acid Analysis in Children Throat-Reliever Granule
Xiaoer Yanbian Keli granules are utilized to treat throat inflammation in children. This brief describes the quantification of the marker compound chlorogenic acid (CA) in a formulated drug.
Oleanolic Acid and Ursonic Acid in Eriobotrya Japonica Leaf
Eriobotrya japonica leaf is widely used as a medicinal material in treatments for a variety of chronic diseases. Key pharmacological components include triterpene acids, two of the marker compounds, oleanolic acid and ursonic acid are assayed in this method.
Paeoniflorin Analysis in Paeoniae Radix Alba
Paeoniflorin is an active component extracted from Paeoniae radix alba, which offers efficacy against gynecological disorders, pain, and hyperactivity of liver-yang, among other disorders. This method is for the quantification of paeoniflorin in herbal plants as per ChP specification.
Oleanlic Acid and Ursonic Acid Analysis of Chaenomelis Fructus
Chaenomeles, the fruit of the Chinese flowering quince, is utilized for its analgesic, anti-inflammatory, antispasmodic and astringent properties, and has also been shown to aid in digestion. Two components of the herbal plant are analyzed, oleanolic acid and ursonic acid.
Common Ginsenosides Found in Ginseng
Many natural products and herbal remedies are produced from the plant panax ginseng, which holds a wide range of medicinal properties such as antioxidant effects and promotion of immune function. Of the main active components, three ginsenosides are analyzed in this ChP method.
Ferulic Acid Analysis in Angelica Sinensis Radix by HPLC
Ferulic acid is an important and valuable phenolic acid whose content is used for assessing the quality of A. sinensis according to the Pharmacopoeia of China (ChP). This application brief outlines the analysis of identified market compound based on ChP.
Tanshinone and Derivatives Analysis in Radix Salviae Miltorrhizae by HPLC
Tanshinones have a variety of biological activities including antiischemic, antioxidant, and antitumor properties. In this work, quantification of tanshinones in herbal plant based on the Chinese Pharmacopoeia method was established.