Introduction
Traditional Chinese medicine (TCM), herbal medicine and other alternative medicines have a rich history of healing and have been practiced for thousands of years. These treatments rely on analytical testing methods to meet pharmacopoeia standards such as Chinese Pharmacopoeia (ChP) and new, 2020 ChP standards. Due to the chemical diversity of TCM ingredients and finished products, chromatographic techniques are important to the characterization and identification needed to meet ChP standards.
Here, we’ve collected widely used TCM workflows utilizing the PerkinElmer UHPLC and SimplicityChrom™ software, LC/MS/MS and Simplicity 3Q™ software, PerkinElmer Epic™ columns, and a variety of chromatography consumables which enable the safety and quality ingredients in TCM products.
Select the TCM application note or brief you wish to download.
LC 300 TCM Resources HUB
Characteristic Components Analysis in Lonicerae Japonica Flos
Lonicera Japonica Flos is a common TCM for treating inflammation and infection disease. This method supports the quality control efforts in the analysis of seven components in Lonicera Japonica Flos samples.
Chlorogenic Acid Analysis in Children Throat-Reliever Granule
Xiaoer Yanbian Keli granules are utilized to treat throat inflammation in children. This brief describes the quantification of the marker compound chlorogenic acid (CA) in a formulated drug.
Oleanolic Acid and Ursonic Acid in Eriobotrya Japonica Leaf
Eriobotrya japonica leaf is widely used as a medicinal material in treatments for a variety of chronic diseases. Key pharmacological components include triterpene acids, two of the marker compounds, oleanolic acid and ursonic acid are assayed in this method.
Paeoniflorin Analysis in Paeoniae Radix Alba
Paeoniflorin is an active component extracted from Paeoniae radix alba, which offers efficacy against gynecological disorders, pain, and hyperactivity of liver-yang, among other disorders. This method is for the quantification of paeoniflorin in herbal plants as per ChP specification.
Oleanlic Acid and Ursonic Acid Analysis of Chaenomelis Fructus
Chaenomeles, the fruit of the Chinese flowering quince, is utilized for its analgesic, anti-inflammatory, antispasmodic and astringent properties, and has also been shown to aid in digestion. Two components of the herbal plant are analyzed, oleanolic acid and ursonic acid.
Common Ginsenosides Found in Ginseng
Many natural products and herbal remedies are produced from the plant panax ginseng, which holds a wide range of medicinal properties such as antioxidant effects and promotion of immune function. Of the main active components, three ginsenosides are analyzed in this ChP method.
Ferulic Acid Analysis in Angelica Sinensis Radix by HPLC
Ferulic acid is an important and valuable phenolic acid whose content is used for assessing the quality of A. sinensis according to the Pharmacopoeia of China (ChP). This application brief outlines the analysis of identified market compound based on ChP.
Tanshinone and Derivatives Analysis in Radix Salviae Miltorrhizae by HPLC
Tanshinones have a variety of biological activities including antiischemic, antioxidant, and antitumor properties. In this work, quantification of tanshinones in herbal plant based on the Chinese Pharmacopoeia method was established.
QSight LC/MS/MS TCM Resources HUB
Analysis of Aflatoxins in Traditional Chinese Medicine Coix Seed Using LC/MS/MS
Coix seed is utilized to enhance immunity, induce diuresis, and strengthen the spleen. This method was developed to detect aflatoxins, a toxic substance that can be found in coix seed, to meet control limits set by ChP.
Rapid Analysis of Gelatinous Traditional Chinese Medicine Using an Epic C18 UHPLC Column
Gelatinous TCMs are claimed to nourish yin, replenish blood and prolong life. This method was developed to identify adulterations per ChP regulated qualitative identification.
Qualitative Identification of Tortoise-Shell Glue Using LC/MS/MS
Tortoise-shell glue is utilized as a health supplement for postpartum women and the elderly. This qualitative identification of tortoise-shell glue was developed to ensure quality and authenticity, and the absence of non-tortoise-shell additives.
An LC/MS/MS Method to Analyze Aristolochic Acid in Traditional Chinese Medicine
Aristolochic acids (AAs) are present in a number of plants and is used to treat symptoms and diseases such as arthritis, gout and inflammation. This method is for the determination of the approved AA, per 2020 ChP amendments.
Workflow for Qualitative Identification of Donkey-Hide Gelatin
Donkey-hide gelatin has been used for centuries to optimize immune response, improve metabolomic balance and treat gynecological diseases. This brief outlines the total workflow solution for the qualitative identification of donkey-hide gelatin following ChP 2020.