Aggravating Aggregates: Amyloid Pathogenicity in Neurodegeneration and Beyond

Within neurodegenerative diseases such as Alzheimer’s or Parkinson’s, great interest currently lies in understanding the behaviour of atypical protein or peptide aggregates, their neurotoxicity, and their potential as therapeutic targets.

In this webinar, researchers Dr. Adriano Aguzzi of University of Zurich and Dr. Ehud Gazit of Tel Aviv University, cover current topics on unnatural aggregates tied to disease pathology, with emphasis on pathogenesis of amyloid aggregates in prion diseases, mechanisms of prion neurotoxicity, and disease modelling using simpler peptide and metabolite assemblies.