MicroCT Breathes New Life Into Pulmonary Research


  • In vivo imaging is a fundamental technique for basic research as well as drug discovery and development offering many benefits including using fewer subjects and the ability to monitor disease state in a single animal over time. MicroCT imaging has shown great potential for analyzing pulmonary morphology and function non-invasively, longitudinally and in 3D. However, imaging of pulmonary mouse models has offered some challenges in the past; the lung’s deep location, it’s highly porous nature, the fast breathing motion and size of the mouse itself, were previously limiting factors. Watch this on demand webinar to learn how researchers at University Medical Center in Göttingen and Chiesi Farmaceutici in Italy used the Quantum microCT system to measure alterations in lung function as well as evaluating how the system was used to study lung fibrosis progression in an IPF-like bleomycin-induced murine model.