PerkinElmer
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Application Brief

Chlorogenic Acid Analysis in Children Throat-Reliever Granule by LC-UV

Introduction

Utilized for throat inflammation in children, Xiaoer Yanbian Keli granules are a traditional Chinese formulated medicine, comprised of the Lonicera Japonica herbal plant. Chinese Pharmacopoeia developed standards in 2020 to ensure quality control, and has finalized the assay of a method in which the specification of the assay of chlorogenic acid is not less than 3 mg per bag.

In this application brief, quantification of the marker compound chlorogenic acid (CA) in a formulated drug, based on Chinese Pharmacopoeia 2020, is presented using a PerkinElmer LC 300 UHPLC with SimplicityChrom software, PerkinElmer Epic C18 column, and additional chromatography consumables.