PerkinElmer
Brief PMS299 D

Application Note

High Sensitivity Methotrexate Quantitation in Human Serum Utilizing

Methotrexate

Introduction

This application note outlines a rapid LC-MS/MS research method utilizing the QSight® 220 triple quadrupole mass spectrometer. The developed method provides exceptional results for the quantitation of methotrexate in serum especially in terms of LLOQs and linearity.