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Application Note

Evolved Gas Analysis: A High Sensitivity Study of a Solvent of Recrystallization in a Pharmaceutical

Introduction

Thermogravimetric analysis (TGA) of materials is commonly used to measure weight loss as a sample is heated or held isothermally. In the pharmaceutical industry, materials often show weight losses associated with the loss of solvent/ water, desolvation or decomposition of the sample. This information is then used to assess the purity and stability of the material and its suitability for use.