PerkinElmer

TR-FRET Toolbox Reagents

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Design your own assay by choosing your preferred donor- and acceptor-labeled reagents. The versatility of LANCE® TR-FRET technology allows the assembly of donor and acceptor dye pairs for use in protein binding and other assays. This is assay design at its most flexible -- featuring the most common affinity biomolecules and europium chelate-labeling reagents.

LANCE toolbox reagents can be used to design a variety of assays, including kinase, protein-protein interaction, protein-nucleic acid interaction, protein-small molecule interaction, epigenetic, receptor-ligand binding, nuclear receptor, receptor dimerization, ubiquitination, and other post-translational modifications, protease, and other binding and enzymatic assays.

Products & Services (88)
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  • Enzymatic (6)
  • Epigenetics (14)
  • Kinase (41)
  • Protein Analysis & Detection (17)
  • Protein-protein interactions (19)
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  • LANCE (20)
  • LANCE SureLight (7)
  • LANCE Ultra (63)
Detection Method
  • Time-Resolved Fluorescence (TRF) (81)
  • TR-FRET (81)
Molecular Modification
  • Acetylation (6)
  • GlcNAc (1)
  • Methylation (9)
  • Phosphorylation (39)

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1-25 of 88 Products & Services

  • PerkinElmer

    LANCE Ultra ULight™-MBP peptide

    Generic peptide substrate for use in TR-FRET biochemical kinase assays. Refer to Selector Guide for validated kinases. MBP peptide (sequence: CFFKNIVTPRTPPPSQGK-amide) labeled with the ULight dye. Human Myelin Basic Protein (MBP) phosphorylation site: Thr232 (Swiss-Prot: P02686); corresponds to Thr98 in other isoforms or species. MBP can be phosphorylated by a variety of kinases including ERK1/ERK2.
    Price Range : 359.00 USD - 979.00 USD
  • LANCE Ulight labeled peptide

    LANCE Ultra ULight™-PLK (Ser137) peptide

    Generic peptide substrate for use in TR-FRET biochemical kinase assays. Refer to Selector Guide for validated kinases. ULight-labeled synthetic peptide containing the amino acid residues surrounding Ser137 of polo-like kinase (PLK). The ULight-PLK peptide can be phosphorylated at Ser137 by a variety of kinases including Aurora A, PAK2, MSK1, PKA and PKC. Peptide core motif: RRRSLLE
    Price Range : 262.00 USD - 950.00 USD
  • LANCE Ultra ULight™-Protein A

    Protein A labeled with ULight™ dye.
    Price Range : 452.00 USD - 979.00 USD
  • LANCE Ulight labeled peptide

    LANCE Ultra ULight™-Tyrosine Hydroxylase (Ser40) peptide

    Generic peptide substrate for use in TR-FRET biochemical kinase assays. Refer to Selector Guide for validated kinases. ULight-labeled synthetic peptide containing the amino acid residues surrounding Ser40 of tyrosine hydoxylase. The ULight-tyrosine hydroxylase peptide can be phosphorylated at Ser40 by a variety of kinases including Aurora A, PAK2, MSK1, PKA and PKC. Peptide core motif: RRQSLIE
    Price Range : 349.00 USD - 950.00 USD
  • LANCE Ultra Europium-anti-methyl-Histone H4 Arginine 3 (H4R3me) Antibody

    Europium-labeled monoclonal antibody recognizing human Histone H4 methylated at arginine3 (H4R3me). For use in LANCE® Ultra epigenetic writer and eraser assays.
    Price Range : 3955.00 USD - 9800.00 USD
  • LANCE Ulight labeled peptide

    LANCE Ultra ULight™-Histone H3 (Thr3/Ser10) Peptide

    Generic peptide substrate for use in TR-FRET biochemical kinase assays. Refer to Selector Guide for validated kinases. ULight-labeled synthetic peptide derived from residues 463-480 of human RAC-alpha serine/threonine-protein kinase (AKT1 or PKB). AKT/PKB can be phosphorylated at Ser473 by the mTOR/Rictor complex and MAPKAP kinase 2. Peptide sequence: ARTKQTARKSTGGK
    Price Range : 333.00 USD - 1360.00 USD
  • LANCE Ultra Europium-anti-phospho-Tyrosine Hydroxylase (Ser40) antibody

    Affinity-purified rabbit polyclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects peptides derived from tyrosine hydroxylase and phosphorylated at serine 40. Tyrosine hydroxylase peptides can be phosphorylated by a variety of kinases including PAK2, PKC, CHK1, Aurora A and PKA. Sequence motif recognized: RRQSLIE
    Price Range : 2318.00 USD - 8000.00 USD
  • LANCE Ultra ULight™-IkappaB-alpha (Ser32/36) peptide

    Generic peptide substrate for use in TR-FRET biochemical kinase assays. Refer to Selector Guide for validated kinases. ULight-labeled synthetic peptide containing the amino acid residues surrounding Ser32/36 of human IkappaB-alpha. The ULight-IkappaB-alpha peptide can be phosphorylated at Ser 32/36 by the IKKβ kinase. Peptide core motif: RHDSGLDSM
    Price Range : 356.00 USD - 969.00 USD
  • LANCE Ultra Europium-anti-phospho-CREB (Ser133)

    Monoclonal antibody labeled with the LANCE® Eu-W1024-ITC chelate. This antibody recognizes specifically phosphorylated Ser133 in the cAMP response element binding (CREB) protein. CREB (Ser 133) can be phosphorylated by a variety of kinases including MSK1, PKA and PKC isoforms.
    Price Range : 1264.00 USD - 5400.00 USD
  • LANCE® Eu-W1024 Anti-Rabbit IgG

    Europium-labeled anti-rabbit IgG, for capturing antibodies in LANCE® TR-FRET assays.
    Price Range : 1183.00 USD - 10300.00 USD
  • LANCE Ulight labeled peptide

    LANCE Ultra ULight-p70 S6K (Thr389) Peptide

    Generic peptide substrate for use in TR-FRET biochemical kinase assays. Refer to Selector Guide for validated kinases. ULight-labeled synthetic peptide containing the amino acid residues surrounding Thr389 of human p70 S6K. The ULight-p70 S6K peptide can be phosphorylated at Thr389 by several kinases including mTOR, COT, HGK, IKKε, IRAK1, IRAK4, MAP4K2, MINK, MST1, MST2, NEK1, NEK2, NEK6, NEK7, PEK, PLK1, and TAOK2. Phosphorylation motif: LGFTYVAP
    Price Range : 333.00 USD - 1360.00 USD
  • LANCE Ultra ULight™-poly GT

    Generic peptide substrate for use in TR-FRET biochemical kinase assays. Refer to Selector Guide for validated kinases. Poly Glu-Tyr (4:1) labeled with ULightTM dye. This random polymer is a Tyrosine kinase substrate.
    Price Range : 359.00 USD - 979.00 USD
  • LANCE Ultra Europium-anti-phospho-IkappaB-alpha (Ser32/36)

    Mouse monoclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects peptides derived from IkappaB-alpha phosphorylated at Ser32/36. IkappaB-alpha (Ser32/36) peptides can be phosphorylated by the IKKβ kinase. Sequence motif recognized: RHDSGLDSM
    Price Range : 1636.00 USD - 5300.00 USD
  • ULight anti-human IgG

    ULight™ labeled anti-human IgG antibody for LANCE® TR-FRET assays. The anti-human IgG antibody is a purified goat polyclonal antibody, and reacts with whole molecule human IgG.
    Price Range : 486.00 USD - 12300.00 USD
  • LANCE Ultra Europium-anti-unmodified Histone H3 Lysine 4 (H3K4) Antibody

    Europium-labeled monoclonal antibody recognizing human Histone
    H3 that is unmodified at lysine 4 (H3K4). For use in LANCE® Ultra epigenetic writer and eraser assays.
    Price Range : 3955.00 USD - 9900.00 USD
  • Europium-labeled antibody for LANCE assays

    LANCE Eu-W1024 Anti-c-Myc

    Europium-labeled anti-c-myc antibody, for capturing c-myc-tagged proteins in LANCE® TR-FRET assays.
    Price Range : 338.00 USD - 16300.00 USD
  • LANCE Ultra Europium-anti-phospho-MEK1/2 (Ser217/221) Antibody

    Rabbit polyclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects human MEK1 phosphorylated at Ser217 and Ser221. It also reacts with MEK1 singly phosphorylated at Ser217 or Ser221. MEK1 is phosphorylated in vivo by RAF1 and COT. Homologous phosphorylation sites are found in MEK2. Sequence motif recognized: GQLIDSMANSFVG
    Price Range : 2476.00 USD - 8000.00 USD
  • Europium-labeled antibody for LANCE assays

    LANCE Eu-W1024 Anti-Mouse IgG

    Europium-labeled anti-mouse IgG, for capturing antibodies in LANCE® TR-FRET assays.
    Price Range : 1183.00 USD - 10300.00 USD
  • LANCE Ultra Europium-anti-phospho-PKC (Ala25Ser) peptide Antibody

    Mouse monoclonal antibody labeled with the LANCE® Europium chelate. This antibody detects phospho-Ser in a synthetic peptide (RFARKGSLRQKNV) only after the peptide is phosphorylated by PKC or PKA kinases. The synthetic peptide is derived from amino acids 19-31 of human PKCα in which Ala25 is mutated to Ser. Sequence motif recognized: RFARKG-pS-LRQKNV
    Price Range : 2319.00 USD - 8000.00 USD
  • ULight Anti-C-tag

    ULight™ labeled anti-C-tag antibodies for LANCE® TR-FRET assays. This mouse monoclonal IgG1 antibody recognizes N-terminal and C-terminal Protein C tagged fusion proteins. The anti-C-tag antibody can be used to capture C-tag proteins, and can be used in conjunction with LANCE Europium-labeled reagents to create LANCE TR-FRET assays.
    Price Range : 494.00 USD - 12000.00 USD
  • LANCE Ultra ULight™-anti-GST

    Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
    Price Range : 534.00 USD - 12600.00 USD
  • LANCE Ultra Europium anti-phospho-Glycogen Synthase (Ser641)

    Europium-labeled rabbit polyclonal antibody recognizing human Muscle Glycogen Synthase phosphorylated at Ser641. Antibody labeled with the LANCE® Eu-W1024-ITC chelate. Sequence motif recognized: PApSVPPSPSL
    Price Range : 2700.00 USD - 8000.00 USD
  • LANCE Ultra Europium-anti-acetyl-Histone H3 Lysine 9 (H3K9ac)

    Europium-labeled monoclonal antibody recognizing human Histone H3 acetylated at lysine 9 (H3K9ac). For use in LANCE® Ultra epigenetic writer and eraser assays.
    Price Range : 3955.00 USD - 9900.00 USD
  • LANCE Ultra ULight™-Streptavidin

    Streptavidin labeled with ULight™ dye.
    Price Range : 359.00 USD - 7000.00 USD
  • ULight anti-mouse IgG

    ULight™ labeled anti-mouse IgG antibody for LANCE® TR-FRET assays. The anti-mouse IgG antibody is a purified goat polyclonal antibody.
    Price Range : 486.00 USD - 12300.00 USD
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