Target selection remains one of the most important decisions and investments that companies make in the drug discovery process. Pursuing the wrong target can waste significant amounts of time and money, and eventually result in failure of the program. To ensure downstream success, targets must be accurately identified and thoroughly validated. Target validation ensures that engagement of the target has potential therapeutic benefit and, along with target identification, is a critical step in the drug development process. A strong link between the target and disease also needs to be demonstrated.
When combined, our in vitro and in vivo technologies provide data on the biological entity associated with the disease of interest and whether appropriate modulation of the target impacts disease in a consistent manner to make the most accurate prediction of target relevance in human disease.
Excellent Sensitivity and Performance for Virtually Any Application
Screening potential candidates is where the journey begins. From target to hit to compound, the transition needs to happen quickly and efficiently. Our drug discovery screening reagents do just that. In addition, our microplate readers are equipped with multiple detection modes to meet the diverse assay requirements of your laboratory for target-based and phenotypic screening. Together, they can provide relevant and reliable results to accelerate your drug discovery process.
Take Your Research Further with Powerful Imaging Analysis
Our high-content screening instruments enable you to perform screens in physiologically and biologically relevant cell systems for more meaningful results. With high-throughput automated imaging and analysis capabilities, these powerful systems produce high-quality images so you can extract quantitative multi-parametric data at the single-cell level in both target-based and phenotypic screening strategies.
Innovative, Integrated Solutions to Accelerate Your Workflow
With dedicated workstations designed for a diverse variety of applications, along with the ability to customize liquid handling workstations based on your needs, our innovative automated liquid handling solutions enable you to minimize errors, reduce hands-on time, and increase throughput and reproducibility. From benchtop application-specific workstations to complex customized integrated solutions, our liquid handing portfolio automates your science.