PerkinElmer

Screening Products

Whether High Throughput or High Content, Screening is an essential part of the drug discovery process.  Advanced technologies available for screening compounds and studying cell images to identify a target’s potential safety and efficacy create a tremendous volume of data.  PerkinElmer’s comprehensive set of screening solutions from image data storage to analysis- available for both on-premises and cloud based applications- are designed to foster collaboration, increase efficiencies, and enable faster processing of even-larger volumes of compounds.

Screening Products

Signals Screening

Intuitive, configurable and flexible screening workflow processor coupled with the unparalleled data visualization and analysis capabilities of TIBCO Spotfire®. Once a screening protocol is set up, raw data from the instruments can be imported directly and processed in a consistent manner.

  • Import raw or processed data from most of the widely performed assay platforms — plate reader, high content reader, surface plasmon resonance, and more.
  • The innovative apps concept allows scientists to create a screening workflow without the reliance on software developers.
  • One Software package for multiple instruments and assay types - saves time and increases data accuracy.

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Columbus™

Instrument agnostic platform for high content image data storage and intuitive, powerful image analysis.

  • Direct integration with Harmony and high content imagers: Opera PhenixTM, Operetta CLSTM.
  • Quickly analyze cellular images for simple and complex phenotypes with flexible building blocks – no scripting required.
  • Collect upwards of 100s of parameters for subsequent multiparametric data analysis and machine learning in High Content Profiler.

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Columbus™ Plus

All of the benefits of Columbus, but with the additional power of high performance cluster computing for scalable storage and real-time image analysis.

  • Reduce image analysis time by 90% and thus overall project time to completion.
  • Increase screening capacity and re-analysis for different end points.
  • Available on premise to leverage existing internal data centers or as a hosted service on the PerkinElmer Cloud.

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High Content Profiler™

Powerful multivariate data analysis and machine learning for high content data analysis and validation in a single easy-to-use platform built on TIBCO Spotfire.

  • Automated, guided workflow from data exploration and QC through hit identification
  • Dimensionality reduction, advanced statistics and machine learning with on-the-fly image rendering for instant validation
  • Integration with ColumbusTM Platform for high content image analysis

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Featured Content

Data Sheet: Signals Screening
PerkinElmer Signals Screening is an intuitive, configurable flexible screening workflow processor coupledwith the unparalleled data visualization and analysis capabilities of TIBCO Spotfire®.

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Application Note: Phenotypic Profiling of Autophagy
In this study we validate a phenotypic image- and data-analysis workflow using our end-to-end integrated HCS platform. Alterations in autophagy are easily visualized using Opera Phenix™ screening system and characterized by a set of advanced features.

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Webinar: Validation & Automation of Phenotypic Profiling
Streamline your workflow and get compounds to the clinic faster. This webinar explores our end-to-end integrated workflow for High Content Screening.

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