Safety & Efficacy

A major stage in biotherapeutic development is to understand the immunogenicity, pharmacokinetics (PK), and pharmacodynamics (PD) of the drug candidate to evaluate both an immune system response as well as in vivo metabolism of the biologic drug, respectively. Interpreting, assessing, and predicting immunogenicity is therefore critical in the development of a biotherapeutic.

Predicting and assessing immunogenicity early in drug discovery ensure the likelihood of success as the biologic drug candidate progresses through the discovery and development pipeline. Pharma and Biopharma companies may have their own proprietary methods for immunogenicity and PK/PD assessment as part of their developability scoring.

PerkinElmer offers a complete solution of tools to help developability scoring, which represents our informatics solution to help predict known sequence activity relationships, to in vivo biodistribution studies and through a variety of immunoassay platforms.

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Biologics Immunogenicity and PK & PD

The immunogenic potential of biotherapeutic drug molecules can have an effect at any point from its administration through metabolism and elimination. Therefore ...

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In Vivo Preclinical Imaging Solutions

Tracking, monitoring, and visualizing biological processes and disease progression is key to not only helping you better understand biology but also crucial in ...

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PerkinElmer’s optimized, automated solutions are designed to improve the efficiency of your genomic workflows. These solutions are designed to eliminate the cha ...

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Explore Our Instrument Solutions

Microplate Readers

As many of you know, microplate readers are instruments used to detect biological, chemical, biochemical or physical events from samples in a microplate. This i ...

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Liquid Handlers

PerkinElmer has been providing liquid handling solutions for over 40 years. A pioneer and innovator in this industry, we offer a comprehensive lineup of robotic ...

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Microfluidic Protein Characterization Analysis

Microfluidic Electrophoresis Analysis Proteins differ from each other in their size, molecular structure and physiochemical properties. These differences allow ...

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