Safety & Efficacy

A major stage in biotherapeutic development is to understand the immunogenicity, pharmacokinetics (PK), and pharmacodynamics (PD) of the drug candidate to evaluate both an immune system response as well as in vivo metabolism of the biologic drug, respectively. Interpreting, assessing, and predicting immunogenicity is therefore critical in the development of a biotherapeutic.

Predicting and assessing immunogenicity early in drug discovery ensure the likelihood of success as the biologic drug candidate progresses through the discovery and development pipeline. Pharma and Biopharma companies may have their own proprietary methods for immunogenicity and PK/PD assessment as part of their developability scoring.

PerkinElmer offers a complete solution of tools to help developability scoring, which represents our informatics solution to help predict known sequence activity relationships, to in vivo biodistribution studies and through a variety of immunoassay platforms.

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Biologics Immunogenicity and PK & PD

The immunogenic potential of biotherapeutic drug molecules can have an effect at any point from its administration through metabolism and elimination. Therefore ...

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In Vivo Preclinical Imaging Solutions

Tracking, monitoring, and visualizing biological processes and disease progression is key to not only helping you better understand biology, but also crucial in ...

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Applied Genomics

PerkinElmer’s optimized, automated solutions are designed to improve the efficiency of your genomic workflows. These solutions are designed to eliminate the cha ...

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GMP Radiosynthesis Services

PerkinElmer's experienced chemists will work with you, scientist to scientist, to design and prepare your radiochemical. You'll have access to PerkinElmer's ext ...

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Explore Our Instrument Solutions

Microplate Readers

Performance, Versatility, and Reliability for Today’s Laboratory Needs As many of you know, microplate readers are instruments used to detect biological, chemic ...

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Automation & Liquid Handling Instruments

With dedicated workstations designed for a diverse variety of applications, along with the ability to customize liquid handling workstations based on your needs ...

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Microfluidic Protein Characterization Analysis

Microfluidic Electrophoresis Analysis Proteins differ from each other in their size, molecular structure and physiochemical properties. These differences allow ...

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