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Assay Target
  • 4-1BB (1)
  • 4-1BBL (2)
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  • STAT1 (7)
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  • TNFα (17)
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  • TrkA (1)
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  • TSH (4)
  • TSLP (2)
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  • VEGF2 Receptor (4)
  • VEGFR1 (2)
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  • Vimentin (2)
  • VISTA (2)
  • Zap70 (4)
  • α-tubulin (3)
  • β-Catenin (1)
  • β-NGF (1)
Target Species
  • Bovine (38)
  • CHO (2)
  • Cynomolgus (4)
  • Human (667)
  • Monkey (2)
  • Mouse (57)
  • Ovine (2)
  • Plant (6)
  • Porcine (16)
  • Rabbit (2)
  • Rat (5)
Application
  • Antibody binding (3)
  • cAMP (33)
  • DNA/RNA Quantitation (1)
  • DNA/RNA Quantitation and QC (15)
  • Drug Discovery & Development (151)
  • Enzymatic (6)
  • Epigenetics (49)
  • High biotin samples (8)
  • Imaging (2)
  • Immunohistochemistry (IHC) (25)
  • In situ hybridization (ISH) (25)
  • In vivo imaging (1)
  • Isotyping (12)
  • Kinase (246)
  • Mass Spectrometry (9)
  • Mobility Shift (36)
  • Molecular Biology (61)
  • Multiplexing (56)
  • Protein Analysis (12)
  • Protein Analysis & Detection (920)
  • Protein-nucleic acid interactions (4)
  • Protein-protein interactions (108)
Therapeutic Area
  • Agriculture/Plant (6)
  • Angiogenesis (62)
  • Arthritis (19)
  • Atherosclerosis (15)
  • Autophagy (5)
  • Bacterial infection (18)
  • Biologics/Bioprocess (75)
  • Cancer (172)
  • Cardiovascular (120)
  • Central Nervous System (129)
  • CNS & Neurologic (19)
  • Diabetes (16)
  • Epigenetics (11)
  • Food Testing (6)
  • Gastrointestinal (43)
  • Inflammation (367)
  • Kidney (2)
  • Metabolic (123)
  • Metabolic Disorders (16)
  • Obesity (2)
  • Oncology/Cancer (23)
  • Pain (45)
  • Renal (2)
  • Vascular disease (5)
  • Virology (5)
Product Brand Name
  • AequoScreen (34)
  • AequoZen (36)
  • Alpha (11)
  • Alpha SureFire Ultra Multiplex (45)
  • AlphaLISA (546)
  • AlphaLISA SureFire Ultra (89)
  • AlphaPlex (39)
  • AlphaScreen (18)
  • AlphaScreen SureFire (71)
  • Ancillary Products (2)
  • Arnel (1)
  • ATPlite 3D (2)
  • Avio (2)
  • AxION (2)
  • BacteriSense (1)
  • Bioware Brite (20)
  • cAMPZen (20)
  • Cat B FAST (2)
  • Cat K FAST (1)
  • CellCarrier (2)
  • Clarus (6)
  • Custodion® (5)
  • DairyGuard (2)
  • DELFIA (20)
  • DropletQuant / LabChip DS (3)
  • EasyTide (23)
  • EnSight (1)
  • EnSpire (2)
  • EnVision (2)
  • FAST Flame (3)
  • FIAS (1)
  • FIMS (1)
  • FMT (3)
  • FolateRSense (1)
  • Frontier (6)
  • G-Platform (2)
  • GastroSense (1)
  • Genhance (4)
  • GFR-Vivo (1)
  • HypoxiSense (1)
  • IntegriSense (3)
  • IVIS (8)
  • JANUS (4)
  • LabChip EZ Reader (49)
  • LabChip GX (13)
  • LabChip GXII (14)
  • LabChip® (1)
  • LAMBDA (14)
  • LANCE (24)
  • LANCE Ultra (35)
  • LANCE SureLight (7)
  • LANCE Ultra (234)
  • Mantra (1)
  • Membrane Target Systems (67)
  • MMPSense (1)
  • NEN (4)
  • NEN Radiochemicals (176)
  • NEN Radiolabeled Ligands (6)
  • NexION (2)
  • OilExpress (4)
  • OilPrep (3)
  • OnPoint (4)
  • Opal (9)
  • Opera Phenix (1)
  • Operetta (29)
  • Operetta CLS (9)
  • Operetta CLS AND Opera Phenix (9)
  • OsteoSense (3)
  • PerkinElmer Signals Lead Discovery (1)
  • PinAAcle (5)
  • ProSense (3)
  • Quantum (1)
  • RediFect (3)
  • ReninSense (1)
  • Sciclone (1)
  • sensilite (2)
  • Spectrum 10 STD (1)
  • Spectrum Adulterant Screen (1)
  • Spectrum Touch Developer (1)
  • Spectrum Two (7)
  • Spectrum Two N (1)
  • SpectrumIMAGE (1)
  • Spotlight (4)
  • Superhance (1)
  • Teledyne CETAC (1)
  • Titan (1)
  • TLectinSense (1)
  • Torion® (5)
  • TSA (12)
  • TSA Plus (14)
  • TurboMatrix (10)
  • twinlite (2)
  • ValiScreen (33)
  • Vectra Polaris (1)
  • Victor (1)
  • VICTOR Nivo (1)
  • ViewLux (1)
  • VivoTag (15)
  • VivoTrack (2)
  • XenoLight (24)
  • Zephyr (1)
Color
  • Black/Clear Bottom (2)
Coating Treatment
  • ULA (2)
Material
  • Cyclic Olefin (2)
Detection Method
  • Absorbance (5)
  • Alpha (815)
  • Brightfield (2)
  • Chromogenic (6)
  • Confocal Imaging (2)
  • DELFIA TRF (19)
  • Fluorescence (41)
  • Fluorescence Intensity (1)
  • Fluorescence Polarization (4)
  • High Content Imaging (2)
  • Image-based Cytometry (1)
  • Luminescence (10)
  • MSI (6)
  • Radiometric (223)
  • Time-Resolved Fluorescence (TRF) (305)
  • TR-FRET (281)
  • Transmission (2)
Molecular Modification
  • Acetylation (13)
  • GlcNAc (1)
  • Glycosidation (1)
  • Methylation (25)
  • Phosphorylation (119)
  • Total (1)
  • Unmodified (4)
Receptor Type
  • 5-Hydroxytryptamine (2)
  • 5-Hydroxytryptamine (Serotonin) (38)
  • Adenosine (18)
  • Adrenergic (14)
  • Anaphylatoxin (1)
  • Angiotensin (7)
  • Bradykinin (5)
  • Calcitonin (1)
  • Cannabinoid (9)
  • Chemokine (28)
  • Dopamine (8)
  • Free Fatty Acid (11)
  • GABA (4)
  • Galanin (10)
  • Ghrelin (1)
  • Glucagon (1)
  • Histamine (17)
  • Inositol Triphosphate (1)
  • Insulin (1)
  • IRK channels (3)
  • Leukotriene (1)
  • Melanocortin (2)
  • Melatonin (2)
  • Motilin (1)
  • Neurotensin (6)
  • Nicotinic (6)
  • Opioid (18)
  • Organic zwitterions/cation transporters (OCTN) (2)
  • Phosphatidylcholine Transfer Protein (PCTP) (2)
  • Prostanoid (10)
  • Retinoic Acid Receptors (1)
  • Tachykinin (1)
  • TRP Channels (3)
  • Urotensin (1)
  • Vasoactive Intestinal Peptide (1)
  • Vasopressin (4)
Assay Validated
  • Binding (130)
  • Calcium Fluorescence (28)
  • Calcium Luminescence (76)
  • cAMP (45)
  • Downstream Phosphorylation (16)
  • GTPγS (32)
  • Inositol Phosphate (6)
Sample Type
  • DNA / RNA (15)
  • Enzyme (38)
  • Protein (12)
Antibody Conjugates
  • Anti-6X His (7)
  • Anti-acetyl-lysine (1)
  • Anti-Acetyl-Lysine (1)
  • Anti-bovine IgA (1)
  • Anti-bovine IgG (1)
  • Anti-bovine IgG1 (1)
  • Anti-bovine IgG2 (1)
  • Anti-bovine IgM (1)
  • Anti-c-Myc (4)
  • Anti-C-tag (3)
  • Anti-DIG (2)
  • Anti-DNP (2)
  • Anti-FITC (4)
  • Anti-FLAG (6)
  • Anti-GFP (2)
  • Anti-goat IgG (1)
  • Anti-GST (5)
  • Anti-H3 (C-term) (1)
  • Anti-H3K27ac (2)
  • Anti-H3K27me2 (1)
  • Anti-H3K27me2-1 (1)
  • Anti-H3K27me3 (2)
  • Anti-H3K36me2 (2)
  • Anti-H3K4 (3)
  • Anti-H3K4me1-2 (2)
  • Anti-H3K9/H3K27 (1)
  • Anti-H3K9/K27 (1)
  • Anti-H3K9ac (2)
  • Anti-H3K9me2 (2)
  • Anti-H3R2me (1)
  • Anti-H4K20me1 (1)
  • Anti-H4R3me (2)
  • Anti-HA (4)
  • Anti-HRP (2)
  • Anti-human IgE (1)
  • Anti-human IgG (6)
  • Anti-human IgG1 (1)
  • Anti-human IgG2 (1)
  • Anti-human IgG3 (1)
  • Anti-human IgG4 (1)
  • Anti-MBP (1)
  • Anti-methyl arginine (1)
  • Anti-methyl-Arg (1)
  • Anti-mouse IgA (1)
  • Anti-mouse IgE (1)
  • Anti-mouse IgG (6)
  • Anti-mouse IgG1 (1)
  • Anti-mouse IgG2a (1)
  • Anti-mouse IgG2b (1)
  • Anti-mouse IgG3 (1)
  • Anti-mouse IgM (1)
  • Anti-O-GlcNAc (1)
  • Anti-O-linked-GlcNAc (1)
  • Anti-P-Ser 14-3-3 (1)
  • Anti-P-Tyr-100 (1)
  • Anti-p53K382ac (2)
  • Anti-phospho-4EBP1 (1)
  • Anti-phospho-Acetyl-CoA-Carboxylase (1)
  • Anti-phospho-Crosstide (1)
  • Anti-phospho-glycogen synthase (1)
  • Anti-phospho-Histone H3 (2)
  • Anti-phospho-I?Ba (1)
  • Anti-phospho-MEK1/2 (1)
  • Anti-phospho-p70S6K (1)
  • Anti-phospho-PKC (1)
  • Anti-phospho-PLK (1)
  • Anti-phospho-rpS6 (1)
  • Anti-phospho-serine (1)
  • Anti-phospho-threonine (1)
  • Anti-phospho-Topo IIa (1)
  • Anti-phospho-Tyrosine Hydroxylase (1)
  • Anti-rabbit IgG (5)
  • Anti-rat IgG (2)
  • Anti-V5 (3)
  • Biotin (1)
  • Glutathione (3)
  • Human Fc-fragment (1)
  • Nickel chelate (1)
  • P-Tyr-100 (1)
  • Protein A (6)
  • Protein G (2)
  • Protein L (1)
  • PT66 (2)
  • PY20 (2)
  • Strep-Tactin (1)
  • Streptavidin (12)
  • Streptavidin/Anti-c-Myc (1)
  • Streptavidin/Anti-DIG (1)
  • Streptavidin/Anti-FITC (1)
  • Streptavidin/Anti-FLAG (1)
  • Streptavidin/Anti-GST (1)
  • Streptavidin/Anti-HA (1)
  • Streptavidin/Anti-mouse IgG (1)
  • Streptavidin/Anti-rabbit IgG (1)
  • Streptavidin/Nickel chelate (1)
  • Streptavidin/P-Tyr-100 (1)
  • Streptavidin/Phosphosensor (1)
  • Streptavidin/Protein A (1)
  • Streptavidin/PT66 (1)
  • Streptavidin/PY20 (1)
  • Unconjugated (2)
Radioisotope
  • Ba-133 (1)
  • C-14 (71)
  • Cr-51 (4)
  • H-3 (90)
  • I-125 (6)
  • P-32 (49)
  • S-35 (4)
Radionuclide
  • 125I (6)
  • 14C (69)
  • 32P (48)
  • 35S (4)
  • 3H (90)
  • 51Cr (4)
Volume Capacity
  • 125 mL (16)
  • 150 µL (2)
Nucleotide
  • ATP (17)
  • CTP (4)
  • dATP (5)
  • dCTP (4)
  • dGTP (2)
  • dTTP (3)
  • GTP (7)
  • NAD (2)
  • pCp (1)
  • UTP (8)
Grade
  • Pure Plus (2)
Fluorescent Agent Type
  • Activatable (9)
  • Cell labeling (2)
  • Labeling (15)
  • Targeted (18)
  • Vascular (10)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy3.5 (1)
  • Cy5 (4)
  • Cy5.5 (1)
  • Eu-N1 (13)
  • Eu-N1-ITC (2)
  • Eu-W1024 (50)
  • Eu-W1024-ITC (1)
  • Eu-W1284-Iodoacetamido (1)
  • Eu-W8044 (1)
  • Eu-W8044-DTA (1)
  • Fluorescein (6)
  • Opal 520 (5)
  • Opal 540 (3)
  • Opal 570 (4)
  • Opal 570 and Opal 690 (1)
  • Opal 620 (3)
  • Opal 650 (3)
  • Opal 670 (1)
  • Opal 690 (3)
  • Sm-N1 (1)
  • SureLight APC (6)
  • SureLight-APC (1)
  • Tb-N1 (1)
  • TMR (5)
  • ULight (27)
Label Position
  • alpha (32)
  • gamma (18)
  • Generally Labeled (2)
  • Nominally Labeled (40)
  • Specifically Labeled (104)
  • Uniformly Labeled (27)
Buffer
  • Aqueous (15)
  • Aqueous PT6-271 Stabilizer (2)
  • EDTA (1)
  • Ethanol 10% (1)
  • Ethanol 2% (1)
  • Ethanol 70% (1)
  • Ethanol : water (11)
  • Ethanol:water (1)
  • HCl (2)
  • Saline (2)
  • Sulfuric acid:ethanol (2)
  • Tricine (25)
  • Tricine with stabilizer and dye (23)
Assay points(200-50,000)
  • 100 (341)
  • 1000 (5)
  • 10000 (329)
  • 300 (1)
  • 500 (649)
  • 5000 (331)
  • 50000 (201)
Assay Target Class
  • Acetylated protein (1)
  • Aminoglycan (2)
  • Antibody (46)
  • Collagen (3)
  • Cytokine (213)
  • DNA (4)
  • Fc-receptor (12)
  • GPCR (176)
  • Histone (11)
  • Hormone (44)
  • Ion channel (3)
  • Peptide (20)
  • Phosphoprotein (175)
  • Protein (401)
  • Receptor (2)
Automation Compatible
  • No (5)
  • Yes (1171)
Concentration
  • 0.02 mCi/mL (1)
  • 0.05 mCi/mL (4)
  • 0.1 mCi/mL (21)
  • 0.2 mCi/mL (4)
  • 0.55 mCi/mL (2)
  • 1 mCi/mL (47)
  • 1 µg/mL (1)
  • 1.0 - 10 mCi/mL (9)
  • 1.12 mCi/mL (1)
  • 10 mCi/mL (27)
  • 100 µg/mL (2)
  • 11.16 mCi/mL (1)
  • 1100 µg/mL (1)
  • 12.5 mCi/mL (2)
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  • Spotlight 200i FT-IR Microscope

    Spotlight 200i FT-IR Microscopy System

    Spotlight 200i FTIR Microscope System is a high-performance microscopy platform, designed to generate high-quality, reproducible data from a variety of sample types.
  • OilExpress_4_XL_220x220

    OilExpress 4 XL

    OilExpress™ 4 system delivers highly automated, rapid, reliable oil condition monitoring results using recognized industry standard protocols such as ASTM®, JOAP and Caterpillar® S•O•S℠.
  • QSight Triple Quad LC-MS

    QSight Pesticide Analyzer

    Built to run hundreds of pesticides in one run, with the utmost sensitivity and efficiency, the QSight Pesticide Analyzer is the only instrument that provides 15% higher throughput than conventional systems.

  • chemagic Prepito

    chemagic Prepito Instrument

    The chemagic Prepito® is based on PerkinElmer’s proven technology for magnetic bead based DNA/RNA isolation and represents a top quality sample preparation system available as a compact benchtop instrument.
  • OilExpress_4_DUO-XL_220x220

    OilExpress 4 XL DUO

    OilExpress™ 4 XL DUO is the ultimate system that delivers highly automated, rapid, reliable oil condition monitoring results using recognized industry standard protocols such as ASTM®, JOAP and Caterpillar® S•O•S℠.
  • FIMS-400 Flow Injection Mercury Analyzer

    FIMS Flow Injection Mercury System

    The FIMS is a compact, easy-to-operate mercury analyzer with an integrated flow injection system for cold vapor mercury AA.
  • EnSight Multimode Plate Reader

    EnSight Multimode Plate Reader

    The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
  • UV Vis | LAMBDA 465 UV/Vis Spectrophotometer

    LAMBDA 465 UV/Vis Spectrophotometer

    Designed specifically for high-end research as well as routine and high-throughput applications, the LAMBDA 465 UV/Vis is the innovative PDA solution that provides maximum reliability – for maximum confidence in your results.
  • JANUS-G3-Standard-8Tip-Varispan-and-MDT-Workstation

    JANUS G3 Varispan + MDT Automated Workstation

    The JANUS® G3 Automated Workstation offers multiple pipetting technologies on a single instrument platform. The instrument consists of a modular platform and combines a flexible 4- or 8-tip Varispan™ arm with 96- or 384-channel Modular Dispense Technology™ (MDT) dispense head, providing an automated liquid handling solution with flexibility in throughput, plate capacity, and dynamic volume range.
  • UV Vis | LAMBDA 365 UV/Vis Spectrophotometer | UV Spectrophotometer

    LAMBDA 365 UV/Vis Spectrophotometer

    The LAMBDA 365 delivers state-of-the-art UV Vis performance that meets the needs of pharmaceuticals, analytic chemists, geneticists, and manufacturing QA/QC analysts everywhere. With 21 CFR part 11 compliant software available, the LAMBDA system is ready to support everything from standard methods and applications to those requiring regulatory compliance.
  • LAMBDA

    LAMBDA 750 UV/Vis/NIR Spectrophotometer

    The LAMBDA 750 is an instrument ideally suited for chemistry and material science applications, busy academic and industrial laboratories that perform measurement of liquids, gels, and solid materials and need flexibility of sampling along with high measurement performance.
  • 1000x1000_Opera_Phenix

    Opera Phenix High-Content Screening System

    The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
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1-12 of 138 Business Insights

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  • Brochure

    Lubricants Analysis - Complete Solutions for Your Lab

    With throughput demands continually increasing, and an ongoing need for more detailed sample information, PerkinElmer systems are setting the standard for speed and productivity in all areas of lubricants analysis: 1.) Wear metals analysis, 2.) Oil condition monitoring and 3.) Confirmatory testing. Modular and scalable, each solution can adapt as your needs change—no matter what the size of your organization or the demands of your application

  • Brochure

    QSight Pesticides Analyzer Brochure

    Pesticides can adversely affect human health through the food we consume but can also leach into soil and groundwater and impact us through the environment. To keep up with a complex and constantly changing regulatory environment, your pesticide analysis solution needs to keep up with your burgeoning sample load.

  • Brochure

    TurboMatrix Thermal Desorbers for Gas Chromatography

    For laboratories analyzing everything from air quality to flavors and fragrances, thermal desorption offers a faster, easier, more cost-efficient way to prepare samples for GC or GC/MS analysis. Ideal for the trace-level measurement of volatile organic compounds (VOCs)—as well as most semi-volatile chemicals—thermal desorption lets you avoid time-consuming, manual, solvent-based sample preparation in favor of a simple, streamlined, automated approach. It also delivers the added benefits of superior throughput and enhanced sensitivity.

  • Brochure

    Clarus 590 and 690 Brochure

    In today’s budget-constrained, yet highly competitive laboratory environments, the samples you’re being asked to analyze – whether food, pharmaceutical, petrochemical, or environmental – are increasingly difficult. But for some labs, having a dedicated GC for every application isn’t an option. For them, a GC that can do it all isn’t just a nice-to have, it’s a necessity

  • Brochure

    The Power of the Sun, Solar Energy Development Solutions

    As the demand for solar power continues to grow, there needs to be a clear focus on different key issues in the life cycle of a solar cell. These issues are: efficiency, durability and cost. Coupling PerkinElmer’s application knowledge and experience together with our product portfolio, we can help manufacturers overcome these obstacles. At PerkinElmer, we’re taking action to ensure the quality of our environment.

  • Brochure

    OilExpress 4 Oil Condition Monitoring System

    The OilExpress 4 system adapts to your laboratory’s needs, from dozens to thousands of samples per day. Its modular design makes it possible to scale up your sample throughput or separately utilize the oil dilution capabilities in busy laboratories that are using ICP analysis. The system minimizes your operational costs by reducing instrument downtime, increasing throughput to reduce cost per sample, and offering significant savings from decreased solvent waste.

  • Product Note

    Torion T-9 GC MS

    Although it was built for portability and speed, the low thermal mass (LTM) capillary GC provides equivalent chromatographic resolution and performance to a benchtop system. The miniature size is achieved by replacing a conventional convectively-heated column oven with a low thermal mass (LTM) column bundle with direct-contact electrical resistive heating. LTM GC uses a small diameter, metal capillary GC column, which is bundled with resistive heating and temperature-sensing wires that are braided Superior technology • Small diameter LTM capillary GC for high speed, high resolution separation of chemical analytes • Rapid temperature programming delivers analysis times of under three min. • Sensitive and selective mass-based detection of a wide range of chemicals • Easy to operate with a color touch-screen display and simple navigation buttons Figure 1. The Torion T-9 Low Thermal Mass Capillary GC is fast and operates reliably. Injection Port with Removable Liner LTM Capillary Column Bundle Cooling Fan Electronic Pressure Control GC Electronic Board together with insulator strands. This design provides for greater heating and cooling speeds and very low power consumption

  • Product Note

    Rapid, Cost-Effective Oil Condition Monitoring -- Spectrum OilExpress System

    Designed specifically to meet the requirements of the Caterpillar® S.O.SSM program, the JOAP program, and the new ASTM® Methods D7412, D7414, D7415, D7418, Spectrum™ OilExpress is the fastest, most cost-effective Oil Condition Monitoring (OCM) solution for busy test laboratories. OilExpress also uses less than half the solvent required by competing systems, dramatically reducing day-to-day operating costs and making laboratories more competitive.

  • Product Note

    Ozone Precursor System

    The analysis of C2 to C12 volatile organic ozone-precursor compounds can present a serious technical challenge to the analytical chemist. Low concentrations in the atmosphere coupled with the need to monitor frequently to assess diurnal variations means that a preconcentration step of the sample before analysis by thermal desorption is required. While the samples can be collected in the field and returned to the laboratory, remote, field-based analysis is desired which allows reduced data turnaround time, minimizes sample collection hardware and permits the presence or absence of VOCs to be correlated with meteorological data. In the field, low-molecular-weight C2 VOCs can be trapped on solid adsorbents if those adsorbents are cryogenically cooled.

  • Guide

    Safeguarding the Authenticity of Herbs & Spices

    Infrared (IR) and near-infrared (NIR) spectroscopy are fast, easy-to-use techniques with a history of being used for food applications such as those for measuring protein, moisture, and fat content. Food fraud and adulteration has become of particular concern to the industry over the past few years following reports of incidents in the media, with herbs and spices identified as one of the key problem areas.

  • White Paper

    Weighing the Benefits and Risks of Nanotechnology White Paper

    There is a growing body of evidence showing that there are significant differences between some nanomaterials and their non-nanoscale counterparts. What those differences portend raises many new questions about their potential to cause harm to human health and the environment.

  • White Paper

    Streamlining Materials Innovation Processes with Electronic Lab Notebook (ELN) and Data Analytics for Optimum Efficiency

    This paper explores the numerous challenges materials scientists and engineers face, from the time it takes to bring new materials to market to the difficulties delivering suitable formulations and testing against specified criteria, and how those can be resolved.

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