For optimized performance from your binding and functional assays, we offer a comprehensive collection of validated fresh cell lines, frozen cells, and membrane preparations. Our cell clones were selected to produce the most effective:
Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
AequoScreen Parental cell stably expressing the mitochondrially targeted apoaequorin gene. GPCRs of your choice can be transiently or stably transfected into these cell lines, for luminescence calcium assays.
Cell membranes expressing recombinant human melatonin MT1 receptor, for ligand binding assays. Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.