Radionuclides provide a highly specific and sensitive labeling option for proteins, cells, and tissues. They are used in a variety of different applications ranging from cellular kinase and transport studies to imaging studies. We offer a wide range of nuclides, stocked at different radioactive concentrations and specific activities to meet your application.
Our radionuclides are used in applications such as:
Protein labeling and pharmacokinetic studies – 125I, 131I
Cellular kinase assays – 32P
Pulse-chase and other studies – 35S, 85Sr
Flux and transport studies – 55Fe, 59Fe, 54Mn, 22Na, 45Ca, 85Rb, 65Zn
Cytotoxicity, ADCC, and CAR-T studies – 51Cr
Radioimmunoassays and imaging studies, 125I, 131I, 45Ca, 57Co
With over 50 years’ experience, you can depend on the chemistry, quality, and selection we offer in our radionuclides.
Chromium-51 (51Cr) radionuclide, commonly used as a label for target cells in chromium release assays, cell-mediated cytotoxicity studies, antibody-dependent cytotoxicity (ADCC) studies, and CAR-T cell development. Target cells uptake 51Cr radionuclide, and release the nuclide into the culture media upon cytolysis or cell death.
Zinc-65 (65Zn) radioactive isotope with a half life of 244 days is used as a tracer to study physical and biological events. A tracer is an isotope whose presence in a system can easily be detected. The isotope is injected into the system at some point. Inside the system, the isotope gives off radiation. That radiation can be followed by means of detectors placed around the system.